Ern Loh, Ph.D.

mutations and human cancer

Lawrence A. Loeb	grad student	2006	University of Washington
(Dissecting genetic and structural determinants of accurate DNA synthesis by DNA polymerase I.)

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Wong A, Kuick CH, Wong WL, et al. (2015) Mutation spectrum of POLE and POLD1 mutations in South East Asian women presenting with Grade 3 endometrioid endometrial carcinomas. Gynecologic Oncology
Ng BG, Sharma V, Sun L, et al. (2011) Identification of the first COG-CDG patient of Indian origin. Molecular Genetics and Metabolism. 102: 364-7
Loh E, Salk JJ, Loeb LA. (2010) Optimization of DNA polymerase mutation rates during bacterial evolution. Proceedings of the National Academy of Sciences of the United States of America. 107: 1154-9
Camps M, Herman A, Loh E, et al. (2007) Genetic constraints on protein evolution. Critical Reviews in Biochemistry and Molecular Biology. 42: 313-26
Loh E, Choe J, Loeb LA. (2007) Highly tolerated amino acid substitutions increase the fidelity of Escherichia coli DNA polymerase I. The Journal of Biological Chemistry. 282: 12201-9
Loh E, Loeb LA. (2005) Mutability of DNA polymerase I: implications for the creation of mutant DNA polymerases. Dna Repair. 4: 1390-8