Jesse J. Salk, Ph.D.

University of Washington, Seattle, Seattle, WA 
mutations and human cancer
"Jesse Salk"
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Lawrence A. Loeb grad student 2010 University of Washington
 (Clonal evolution in cancer.)
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LeBlanc DPM, Meier M, Lo FY, et al. (2022) Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations. Bmc Genomics. 23: 542
Zhang Y, Kohrn BF, Yang M, et al. (2021) PolyG-DS: An ultrasensitive polyguanine tract-profiling method to detect clonal expansions and trace cell lineage. Proceedings of the National Academy of Sciences of the United States of America. 118
Valentine CC, Young RR, Fielden MR, et al. (2020) Direct quantification of in vivo mutagenesis and carcinogenesis using duplex sequencing. Proceedings of the National Academy of Sciences of the United States of America
Short NJ, Kantarjian H, Kanagal-Shamanna R, et al. (2020) Ultra-accurate Duplex Sequencing for the assessment of pretreatment ABL1 kinase domain mutations in Ph+ ALL. Blood Cancer Journal. 10: 61
Higgins J, Williams LN, Valentine CC, et al. (2020) Abstract PR04: Clonal landscapes of hematologic malignancies redefined by ultrasensitive duplex sequencing Clinical Cancer Research. 26
Lo FY, Valentine C, Schmidt E, et al. (2020) Abstract 3147: Non-invasive detection of aristolochic acid exposure using ultra-sensitive duplex sequencing Clinical Trials
Loeb LA, Kohrn BF, Loubet-Senear KJ, et al. (2019) Extensive subclonal mutational diversity in human colorectal cancer and its significance. Proceedings of the National Academy of Sciences of the United States of America
Salk JJ, Kennedy SR. (2019) Next-Generation Genotoxicology: Using Modern Sequencing Technologies to Assess Somatic Mutagenesis and Cancer Risk. Environmental and Molecular Mutagenesis
Salk JJ, Loubet-Senear K, Maritschnegg E, et al. (2019) Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan. Cell Reports. 28: 132-144.e3
Higgins J, Pratt G, Valentine CC, et al. (2019) Redefining "Gold Standard": Ultra-Sensitive Characterization of Commercial DNA Standards with Duplex Sequencing Blood. 134: 2093-2093
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