Heidi L. Holtorf, Ph.D.

Affiliations: 
Rice University, Houston, TX 
Area:
biomaterials for use as scaffolds for tissue engineering, as carriers for controlled drug delivery, and as non-viral vectors for gene therapy
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"Heidi Holtorf"
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Antonios Georgios Mikos grad student 2005 Rice University
 (Modulation of marrow stromal cell differentiation in bone tissue engineering constructs.)
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Publications

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Holtorf HL, Jansen JA, Mikos AG. (2006) Modulation of cell differentiation in bone tissue engineering constructs cultured in a bioreactor. Advances in Experimental Medicine and Biology. 585: 225-41
Gomes ME, Holtorf HL, Reis RL, et al. (2006) Influence of the porosity of starch-based fiber mesh scaffolds on the proliferation and osteogenic differentiation of bone marrow stromal cells cultured in a flow perfusion bioreactor. Tissue Engineering. 12: 801-9
Chang RC, Starly B, Culbertson C, et al. (2006) Development of an in vitro micro-organ model for pharmacokinetic microanalysis Bioengineering, Proceedings of the Northeast Conference. 2006: 183-184
Chang R, Starly B, Sun W, et al. (2006) Freeform bioprinting of liver encapsulated in alginate hydrogels tissue constructs for pharmacokinetic study 17th Solid Freeform Fabrication Symposium, Sff 2006. 138-147
Holtorf HL, Sheffield TL, Ambrose CG, et al. (2005) Flow perfusion culture of marrow stromal cells seeded on porous biphasic calcium phosphate ceramics. Annals of Biomedical Engineering. 33: 1238-48
Holtorf HL, Datta N, Jansen JA, et al. (2005) Scaffold mesh size affects the osteoblastic differentiation of seeded marrow stromal cells cultured in a flow perfusion bioreactor. Journal of Biomedical Materials Research. Part A. 74: 171-80
Holtorf HL, Jansen JA, Mikos AG. (2005) Ectopic bone formation in rat marrow stromal cell/titanium fiber mesh scaffold constructs: effect of initial cell phenotype. Biomaterials. 26: 6208-16
Holtorf HL, Jansen JA, Mikos AG. (2005) Flow perfusion culture induces the osteoblastic differentiation of marrow stroma cell-scaffold constructs in the absence of dexamethasone. Journal of Biomedical Materials Research. Part A. 72: 326-34
Datta N, Holtorf HL, Sikavitsas VI, et al. (2005) Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells. Biomaterials. 26: 971-7
Datta N, Holtorf HL, Jansen JA, et al. (2004) In vitro synthesis of osteoinductive extracellular matrix for bone tissue engineering Transactions - 7th World Biomaterials Congress. 1016
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