Jonathan A. Ewald, Ph.D.

Vanderbilt University, Nashville, TN 
protein structure & function, signal transduction
"Jonathan Ewald"
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James V. Staros grad student 1997-2001 Vanderbilt
 (Roles of the kinase domain in epidermal growth factor receptor signaling: Comparison of wild type and kinase -impaired mutant receptor function.)
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Bauman TM, Ewald JA, Huang W, et al. (2015) CD147 expression predicts biochemical recurrence after prostatectomy independent of histologic and pathologic features. Bmc Cancer. 15: 549
Ewald JA, Downs TM, Cetnar JP, et al. (2013) Expression microarray meta-analysis identifies genes associated with Ras/MAPK and related pathways in progression of muscle-invasive bladder transition cell carcinoma. Plos One. 8: e55414
Desotelle J, Truong M, Ewald J, et al. (2013) CpG island hypermethylation frequently silences FILIP1L isoform 2 expression in prostate cancer Journal of Urology. 189: 329-335
Ewald JA, Desotelle JA, Church DR, et al. (2013) Androgen deprivation induces senescence characteristics in prostate cancer cells in vitro and in vivo Prostate. 73: 337-345
Shankaran H, Zhang Y, Chrisler WB, et al. (2012) Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics Molecular Biosystems. 8: 2868-2882
Ewald JA, Jarrard DF. (2012) Decreased skp2 expression is necessary but not sufficient for therapy-induced senescence in prostate cancer Translational Oncology. 5: 278-287
Ewald JA, Desotelle JA, Wilding G, et al. (2010) Therapy-induced senescence in cancer. Journal of the National Cancer Institute. 102: 1536-46
Ewald JA, Peters N, Desotelle JA, et al. (2009) A high-throughput method to identify novel senescence-inducing compounds. Journal of Biomolecular Screening. 14: 853-8
Fu VX, Dobosy JR, Desotelle JA, et al. (2008) Aging and cancer-related loss of insulin-like growth factor 2 imprinting in the mouse and human prostate. Cancer Research. 68: 6797-802
Ewald JA, Desotelle JA, Almassi N, et al. (2008) Drug-induced senescence bystander proliferation in prostate cancer cells in vitro and in vivo British Journal of Cancer. 98: 1244-1249
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