Handan Kaygun, Ph.D.

RNA Biology

William F. Marzluff	grad student	2005	UNC Chapel Hill
(The mechanism of histone mRNA degradation following the inhibition of DNA synthesis.)

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Mullen TE, Kaygun H, Marzluff WF. (2008) Chapter 2 Cell-Cycle Regulation of Histone mRNA Degradation in Mammalian Cells. Role of Translation and Oligouridylation Methods in Enzymology. 449: 23-45
Kaygun H, Marzluff WF. (2005) Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1 Nature Structural and Molecular Biology. 12: 794-800
Kaygun H, Marzluff WF. (2005) Translation termination is involved in histone mRNA degradation when DNA replication is inhibited Molecular and Cellular Biology. 25: 6879-6888
Whitfield ML, Kaygun H, Erkmann JA, et al. (2004) SLBP is associated with histone mRNA on polyribosomes as a component of the histone mRNP Nucleic Acids Research. 32: 4833-4842
Dominski Z, Yang XC, Kaygun H, et al. (2003) A 3′ exonuclease that specifically interacts with the 3′ end of histone mRNA Molecular Cell. 12: 295-305
Lanzotti DJ, Kaygun H, Yang X, et al. (2002) Developmental control of histone mRNA and dSLBP synthesis during Drosophila embryogenesis and the role of dSLBP in histone mRNA 3' end processing in vivo. Molecular and Cellular Biology. 22: 2267-82