Thomas E. Mullen, Ph.D.

Affiliations: 
Biochemistry and Biophysics University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
RNA Biology
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"Thomas Mullen"
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Parents

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William F. Marzluff grad student 2008 UNC Chapel Hill
 (Pathway of histone mRNA degradation: Oligouridylation followed by bidirectional decay.)
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Publications

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Edvardson S, Nicolae CM, Agrawal PB, et al. (2017) Heterozygous De Novo UBTF Gain-of-Function Variant Is Associated with Neurodegeneration in Childhood. American Journal of Human Genetics. 101: 267-273
Gray JM, Harmin DA, Boswell SA, et al. (2014) SnapShot-Seq: a method for extracting genome-wide, in vivo mRNA dynamics from a single total RNA sample. Plos One. 9: e89673
Sullivan KD, Mullen TE, Marzluff WF, et al. (2009) Knockdown of SLBP results in nuclear retention of histone mRNA. Rna (New York, N.Y.). 15: 459-72
Mullen TE, Kaygun H, Marzluff WF. (2008) Chapter 2 Cell-Cycle Regulation of Histone mRNA Degradation in Mammalian Cells. Role of Translation and Oligouridylation Methods in Enzymology. 449: 23-45
Mullen TE, Marzluff WF. (2008) Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5′ to 3′ and 3′ to 5′ Genes and Development. 22: 50-65
Zhou T, Chou J, Mullen TE, et al. (2007) Identification of primary transcriptional regulation of cell cycle-regulated genes upon DNA damage. Cell Cycle (Georgetown, Tex.). 6: 972-81
Zhou T, Chou JW, Simpson DA, et al. (2006) Profiles of global gene expression in ionizing-radiation-damaged human diploid fibroblasts reveal synchronization behind the G1 checkpoint in a G0-like state of quiescence. Environmental Health Perspectives. 114: 553-9
Unsal-Kaçmaz K, Mullen TE, Kaufmann WK, et al. (2005) Coupling of human circadian and cell cycles by the timeless protein. Molecular and Cellular Biology. 25: 3109-16
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