Luke A. Moe, Ph.D.

Institution:
University of Wisconsin, Madison, Madison, WI
Area:
Biochemical, catalytic, and spectroscopic studies of redox active enzymes; protein engineering
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"Luke Moe"
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Brian G. Fox grad student 2005 UW Madison
 (Catalytic studies and component interactions of the toluene -4 -monooxygenase from Pseudomonas mendocina KR1.)
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Publications

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Rozhkova-Novosad EA, Chae JC, Zylstra GJ, et al. (2007) Profiling mechanisms of alkane hydroxylase activity in vivo using the diagnostic substrate norcarane. Chemistry & Biology. 14: 165-72
Elsen NL, Moe LA, McMartin LA, et al. (2007) Redox and functional analysis of the Rieske ferredoxin component of the toluene 4-monooxygenase. Biochemistry. 46: 976-86
Moe LA, McMartin LA, Fox BG. (2006) Component interactions and implications for complex formation in the multicomponent toluene 4-monooxygenase. Biochemistry. 45: 5478-85
Moe LA, Bingman CA, Wesenberg GE, et al. (2006) Structure of T4moC, the Rieske-type ferredoxin component of toluene 4-monooxygenase. Acta Crystallographica. Section D, Biological Crystallography. 62: 476-82
Moe LA, Fox BG. (2005) Oxygen-18 tracer studies of enzyme reactions with radical/cation diagnostic probes. Biochemical and Biophysical Research Communications. 338: 240-9
Bertrand E, Sakai R, Rozhkova-Novosad E, et al. (2005) Reaction mechanisms of non-heme diiron hydroxylases characterized in whole cells. Journal of Inorganic Biochemistry. 99: 1998-2006
Kemner KM, Kelly SD, O'Loughlin EJ, et al. (2005) XRF and XAFS analysis of electrophoretically isolated nondenatured proteins Physica Scripta T. 940-942
Moe LA, Hu Z, Deng D, et al. (2004) Remarkable aliphatic hydroxylation by the diiron enzyme toluene 4-monooxygenase in reactions with radical or cation diagnostic probes norcarane, 1,1-dimethylcyclopropane, and 1,1-diethylcyclopropane. Biochemistry. 43: 15688-701
Skjeldal L, Peterson FC, Doreleijers JF, et al. (2004) Solution structure of T4moC, the Rieske ferredoxin component of the toluene 4-monooxygenase complex. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 9: 945-53
Luo W, Moe LA, Skjeldal L, et al. (2001) Assignment of 1H, 13C and 15N NMR signals from toluene 4-monooxygenase Rieske ferredoxin in its oxidized state. Journal of Biomolecular Nmr. 21: 73-4
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