Nathaniel L. Elsen, Ph.D.

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
Area:
Biochemical, catalytic, and spectroscopic studies of redox active enzymes; protein engineering
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"Nathaniel Elsen"
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Brian G. Fox grad student 2008 UW Madison
 (The effects of protein -protein interactions on the steady state and pre-steady state kinetics of toluene 4-monooxygenase.)
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Publications

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Elsen NL, Patel SB, Ford RE, et al. (2017) Insights into activity and inhibition from the crystal structure of human O-GlcNAcase. Nature Chemical Biology
Acheson JF, Bailey LJ, Elsen NL, et al. (2014) Structural basis for biomolecular recognition in overlapping binding sites in a diiron enzyme system Nature Communications. 5
Takasuka TE, Walker JA, Bergeman LF, et al. (2014) Cell-free translation of biofuel enzymes. Methods in Molecular Biology (Clifton, N.J.). 1118: 71-95
Bailey LJ, Acheson JF, McCoy JG, et al. (2012) Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase. Biochemistry. 51: 1101-13
Bianchetti CM, Elsen NL, Fox BG, et al. (2011) Structure of cellobiose phosphorylase from Clostridium thermocellum in complex with phosphate Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 67: 1345-1349
Riederer A, Takasuka TE, Makino S, et al. (2011) Global gene expression patterns in Clostridium thermocellum as determined by microarray analysis of chemostat cultures on cellulose or cellobiose. Applied and Environmental Microbiology. 77: 1243-53
Elsen NL, Bailey LJ, Hauser AD, et al. (2009) Role for threonine 201 in the catalytic cycle of the soluble diiron hydroxylase toluene 4-monooxygenase Biochemistry. 48: 3838-3846
Levin EJ, Elsen NL, Seder KD, et al. (2008) X-ray structure of a soluble Rieske-type ferredoxin from Mus musculus. Acta Crystallographica. Section D, Biological Crystallography. 64: 933-40
Bailey LJ, Elsen NL, Pierce BS, et al. (2008) Soluble expression and purification of the oxidoreductase component of toluene 4-monooxygenase. Protein Expression and Purification. 57: 9-16
Elsen NL, Moe LA, McMartin LA, et al. (2007) Redox and functional analysis of the Rieske ferredoxin component of the toluene 4-monooxygenase. Biochemistry. 46: 976-86
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