Timothy M. Acker, Ph.D.
Institution:
Emory University, Atlanta, GAArea:
Medicinal, Bioorganic, Synthetic Organic, ComputationalGoogle:
"Timothy Acker"Mean distance: 9.82 | S | N | B | C | P |
Parents
Sign in to add mentor| Dennis C. Liotta | grad student | 2013 | Emory | |
| (Structural Determinants of Activity, Mechanism and Structure Activity Relationships of Novel GluN2C/D Subunit Selective Antagonists of the N-methyl-D-Aspartate Receptor.) | ||||
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Publications
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| D'Erasmo MP, Akins NS, Ma P, et al. (2023) Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the -Methyl-d-aspartate Receptor. Acs Chemical Neuroscience |
| Swanger SA, Vance KM, Acker TM, et al. (2017) A novel negative allosteric modulator selective for GluN2C/2D-containing NMDA receptors inhibits synaptic transmission in hippocampal interneurons. Acs Chemical Neuroscience |
| Gable JE, Lee GM, Acker TM, et al. (2016) Fragment-Based Protein-Protein Interaction Antagonists of a Viral Dimeric Protease. Chemmedchem |
| Acker TM, Khatri A, Vance KM, et al. (2013) Structure-activity relationships and pharmacophore model of a noncompetitive pyrazoline containing class of GluN2C/GluN2D selective antagonists. Journal of Medicinal Chemistry. 56: 6434-56 |
| Santangelo RM, Acker TM, Zimmerman SS, et al. (2012) Novel NMDA receptor modulators: an update. Expert Opinion On Therapeutic Patents. 22: 1337-52 |
| Acker TM, Yuan H, Hansen KB, et al. (2011) Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators. Molecular Pharmacology. 80: 782-95 |
| Mosley CA, Acker TM, Hansen KB, et al. (2010) Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists. Journal of Medicinal Chemistry. 53: 5476-90 |