Margaret D. Myers, Ph.D.

Signal transduction in lymphocytes

Arthur Weiss	grad student	2005	UCSF
(Src -like adaptor protein: A molecule that regulates TCR/CD3 expression by adapting the E3 ubiquitin ligase c -Cbl to the TCR/CD3 complex.)

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Dragone LL, Shaw LA, Myers MD, et al. (2009) SLAP, a regulator of immunoreceptor ubiquitination, signaling, and trafficking. Immunological Reviews. 232: 218-28
Dragone LL, Myers MD, White C, et al. (2006) Src-like adaptor protein (SLAP) regulates B cell receptor levels in a c-Cbl-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 103: 18202-7
Dragone LL, Myers MD, White C, et al. (2006) SRC-like adaptor protein regulates B cell development and function. Journal of Immunology (Baltimore, Md. : 1950). 176: 335-45
Myers MD, Sosinowski T, Dragone LL, et al. (2006) Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex. Nature Immunology. 7: 57-66
Myers MD, Dragone LL, Weiss A. (2005) Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation. The Journal of Cell Biology. 170: 285-94