Wanli Lu, Ph.D.

Affiliations: 
Oregon State University, Corvallis, OR 
Area:
Natural Products Drug Discovery, Biosynthesis
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"Wanli Lu"
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SNBCP

Parents

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Taifo Mahmud grad student 2012 Oregon State
 (Biosynthetic Engineering of New Pactamycins.)
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Publications

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Kim SH, Lu W, Ahmadi MK, et al. (2018) Atolypenes, Tricyclic Bacterial Sesterterpenes Discovered Using a Multiplexed In Vitro Cas9-TAR Gene Cluster Refactoring Approach. Acs Synthetic Biology
Lu W, Alanzi AR, Abugrain ME, et al. (2018) Global and pathway-specific transcriptional regulations of pactamycin biosynthesis in Streptomyces pactum. Applied Microbiology and Biotechnology
Abugrain ME, Lu W, Li Y, et al. (2016) Interrogating the Tailoring Steps of Pactamycin Biosynthesis and Accessing New Pactamycin Analogues. Chembiochem : a European Journal of Chemical Biology
Abugrain ME, Lu W, Li Y, et al. (2016) Cover Picture: Interrogating the Tailoring Steps of Pactamycin Biosynthesis and Accessing New Pactamycin Analogues (ChemBioChem 17/2016) Chembiochem. 17: 1579
Guha G, Lu W, Li S, et al. (2015) Novel Pactamycin Analogs Induce p53 Dependent Cell-Cycle Arrest at S-Phase in Human Head and Neck Squamous Cell Carcinoma (HNSCC) Cells. Plos One. 10: e0125322
Kancharla P, Lu W, Salem SM, et al. (2014) Stereospecific synthesis of 23-hydroxyundecylprodiginines and analogues and conversion to antimalarial premarineosins via a Rieske oxygenase catalyzed bicyclization. The Journal of Organic Chemistry. 79: 11674-89
Salem SM, Kancharla P, Florova G, et al. (2014) Elucidation of final steps of the marineosins biosynthetic pathway through identification and characterization of the corresponding gene cluster. Journal of the American Chemical Society. 136: 4565-74
Almabruk KH, Lu W, Li Y, et al. (2013) Mutasynthesis of fluorinated pactamycin analogues and their antimalarial activity Organic Letters. 15: 1678-1681
Lu W, Roongsawang N, Mahmud T. (2011) Biosynthetic studies and genetic engineering of pactamycin analogs with improved selectivity toward malarial parasites. Chemistry & Biology. 18: 425-31
Ito T, Roongsawang N, Shirasaka N, et al. (2009) Deciphering pactamycin biosynthesis and engineered production of new pactamycin analogues. Chembiochem : a European Journal of Chemical Biology. 10: 2253-65
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