Julie M. Lowe, Ph.D.

Biochemistry & Molecular Georgetown University, Washington, DC 
"Julie Lowe"
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Albert J. Fornace grad student 2010 Georgetown
 (Identification of NF-kappaB and DNA-dependent protein kinase (DNA-PK) as new players in the regulation and signaling of the oncogenic phosphatase Wip1.)
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Aloor JJ, Azzam KM, Guardiola JJ, et al. (2018) Leucine-Rich Repeats and Calponin Homology containing 4 regulates the innate immune response. The Journal of Biological Chemistry
Lowe JM, Nguyen TA, Grimm SA, et al. (2016) The novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression. Cell Death and Differentiation
Menendez D, Lowe JM, Snipe J, et al. (2016) Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells. Oncotarget
Lowe JM, Menendez D, Fessler MB. (2014) A new inflammatory role for p53 in human macrophages. Cell Cycle (Georgetown, Tex.). 13: 2983-4
Lowe JM, Menendez D, Bushel PR, et al. (2014) p53 and NF-κB coregulate proinflammatory gene responses in human macrophages. Cancer Research. 74: 2182-92
Madenspacher JH, Azzam KM, Gowdy KM, et al. (2013) p53 Integrates host defense and cell fate during bacterial pneumonia. The Journal of Experimental Medicine. 210: 891-904
Lowe J, Cha H, Lee MO, et al. (2012) Regulation of the Wip1 phosphatase and its effects on the stress response. Frontiers in Bioscience (Landmark Edition). 17: 1480-98
Cha H, Lowe JM, Li H, et al. (2010) Wip1 directly dephosphorylates γ-H2AX and attenuates the DNA damage response Cancer Research. 70: 4112-4122
Lowe JM, Cha H, Yang Q, et al. (2010) Nuclear factor-κB (NF-κB) is a novel positive transcriptional regulator of the oncogenic Wip1 phosphatase Journal of Biological Chemistry. 285: 5249-5257
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