John B. Jordan, Ph.D.

Affiliations: 
University of Arkansas, Little Rock, AR 
Area:
metal cation NMR spectroscopy
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"John Jordan"
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James F. Hinton grad student 2004 University of Arkansas
 (The effects of single amino acid replacements on the structure and function of the gramicidin A ion channel determined using nuclear magnetic resonance spectroscopy and single -channel conductance measurements.)
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Publications

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Brinson RG, Marino JP, Delaglio F, et al. (2018) Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics. Mabs
Moyer BD, Murray JK, Ligutti J, et al. (2018) Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V. Plos One. 13: e0196791
Jordan JB, Whittington DA, Bartberger MD, et al. (2016) A Fragment Linking Approach Using 19F NMR Spectroscopy to Obtain Highly Potent and Selective Inhibitors of β-secretase. Journal of Medicinal Chemistry
Poppe L, Jordan JB, Rogers G, et al. (2015) On the Analytical Superiority of 1D NMR for Fingerprinting the Higher Order Structure of Protein Therapeutics Compared to Multidimensional NMR Methods. Analytical Chemistry. 87: 5539-45
Poppe L, Jordan JB, Lawson K, et al. (2013) Profiling formulated monoclonal antibodies by (1)H NMR spectroscopy. Analytical Chemistry. 85: 9623-9
Michelsen K, Jordan JB, Lewis J, et al. (2012) Ordering of the N-terminus of human MDM2 by small molecule inhibitors. Journal of the American Chemical Society. 134: 17059-67
Jordan JB, Poppe L, Xia X, et al. (2012) Fragment based drug discovery: practical implementation based on ¹⁹F NMR spectroscopy. Journal of Medicinal Chemistry. 55: 678-87
Michelsen K, Jordan J, Lewis J, et al. (2012) NMR Structure of Mdm2 (6-125) with Pip-1 Journal of Back and Musculoskeletal Rehabilitation
Beel AJ, Barrett P, Schnier PD, et al. (2009) Nonspecificity of binding of gamma-secretase modulators to the amyloid precursor protein. Biochemistry. 48: 11837-9
Jordan JB, Poppe L, Haniu M, et al. (2009) Hepcidin revisited, disulfide connectivity, dynamics, and structure. The Journal of Biological Chemistry. 284: 24155-67
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