Sean F. O'Hearn, Ph.D.
Affiliations: | Johns Hopkins University, Baltimore, MD |
Area:
RNA editing, and processing of DNA sequencesGoogle:
"Sean O'Hearn"Mean distance: 9.56 | S | N | B | C | P |
Parents
Sign in to add mentor| Barbara Sollner-Webb | grad student | 2004 | Johns Hopkins | |
| (Characterization of the seven major polypeptides of the Trypanosoma brucei mitochondrial RNA editing complex.) | ||||
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Publications
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| Law JA, O'Hearn SF, Sollner-Webb B. (2008) Trypanosoma brucei RNA editing protein TbMP42 (band VI) is crucial for the endonucleolytic cleavages but not the subsequent steps of U-deletion and U-insertion. Rna (New York, N.Y.). 14: 1187-200 |
| Law JA, O'Hearn S, Sollner-Webb B. (2007) In Trypanosoma brucei RNA editing, TbMP18 (band VII) is critical for editosome integrity and for both insertional and deletional cleavages. Molecular and Cellular Biology. 27: 777-87 |
| Zhelonkina AG, O'Hearn SF, Law JA, et al. (2006) T. brucei RNA editing: action of the U-insertional TUTase within a U-deletion cycle. Rna (New York, N.Y.). 12: 476-87 |
| Law JA, Huang CE, O'Hearn SF, et al. (2005) In Trypanosoma brucei RNA editing, band II enables recognition specifically at each step of the U insertion cycle. Molecular and Cellular Biology. 25: 2785-94 |
| O'Hearn SF, Huang CE, Hemann M, et al. (2003) Trypanosoma brucei RNA editing complex: band II is structurally critical and maintains band V ligase, which is nonessential. Molecular and Cellular Biology. 23: 7909-19 |
| Huang CE, O'Hearn SF, Sollner-Webb B. (2002) Assembly and function of the RNA editing complex in Trypanosoma brucei requires band III protein. Molecular and Cellular Biology. 22: 3194-203 |
| Huang CE, Cruz-Reyes J, Zhelonkina AG, et al. (2001) Roles for ligases in the RNA editing complex of Trypanosoma brucei: band IV is needed for U-deletion and RNA repair. The Embo Journal. 20: 4694-703 |