Julie A. Zorn, Ph.D.
Affiliations: | Chemistry and Chemical Biology | University of California, San Francisco, San Francisco, CA |
Area:
molecular recognitionGoogle:
"Julie Zorn"Mean distance: 9.91 | S | N | B | C | P |
Parents
Sign in to add mentor| James A. Wells | grad student | 2012 | UCSF | |
| (Activation of Apoptotic Procaspases.) | ||||
| John Kuriyan | post-doc | 2012-2014 | UC Berkeley | |
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Publications
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| Zorn JA, Wang Q, Fujimura E, et al. (2015) Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220). Plos One. 10: e0121177 |
| Wang Q, Vogan EM, Nocka LM, et al. (2015) Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate. Elife. 4 |
| Kovacs E, Zorn JA, Huang Y, et al. (2015) A structural perspective on the regulation of the epidermal growth factor receptor. Annual Review of Biochemistry. 84: 739-64 |
| Kovacs E, Zorn JA, Huang Y, et al. (2015) A structural perspective on the regulation of the epidermal growth factor receptor Annual Review of Biochemistry. 84: 739-764 |
| Wang Q, Zorn JA, Kuriyan J. (2014) A structural at~las of kinases inhibited by clinically approved drugs Methods in Enzymology. 548: 23-67 |
| Julien O, Kampmann M, Bassik MC, et al. (2014) Unraveling the mechanism of cell death induced by chemical fibrils. Nature Chemical Biology. 10: 969-76 |
| Julien O, Kampmann M, Bassik MC, et al. (2014) Unraveling the Mechanism of Cell Death Induced by Chemical and Protein Fibrils Biophysical Journal. 106: 40a |
| Zorn JA, Wolan DW, Agard NJ, et al. (2012) Fibrils colocalize caspase-3 with procaspase-3 to foster maturation. The Journal of Biological Chemistry. 287: 33781-95 |
| Zorn JA, Wille H, Wolan DW, et al. (2011) Self-assembling small molecules form nanofibrils that bind procaspase-3 to promote activation. Journal of the American Chemical Society. 133: 19630-3 |
| Zorn JA, Wells JA. (2010) Turning enzymes ON with small molecules. Nature Chemical Biology. 6: 179-188 |