Kevin C. Slep, Ph.D.

Yale University, New Haven, CT 
Protein Folding and Dynamics, Structural Biology
"Kevin Slep"
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Andrew D. Miranker grad student 2000 Yale
 (Structural investigations of the regulator of G -protein signaling family of GTPase activating proteins.)
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McParland ED, Butcher TA, Gurley NJ, et al. (2024) Canoe's Dilute domain is not essential for linking cell junctions to the cytoskeleton but supports morphogenesis robustness. Journal of Cell Science
Bolhuis DL, Dixit R, Slep KC. (2023) Crystal structure of the Arabidopsis SPIRAL2 C-terminal domain reveals a p80-Katanin-like domain. Plos One. 18: e0290024
Fan Y, Bilkey N, Bolhuis DL, et al. (2023) A divergent TOG domain and oligomerization contribute to SPIRAL2 function in stabilizing microtubule minus ends. The Plant Cell
McParland ED, Butcher TA, Gurley NJ, et al. (2023) The Dilute domain of Canoe is not essential for Canoe's role in linking adherens junctions to the cytoskeleton but contributes to robustness of morphogenesis. Biorxiv : the Preprint Server For Biology
Ryniawec JM, Buster DW, Slevin LK, et al. (2023) Polo-like kinase 4 homodimerization and condensate formation regulate its own protein levels but are not required for centriole assembly. Molecular Biology of the Cell. mbcE22120572
Perez-Vale KZ, Yow KD, Johnson RI, et al. (2021) Multivalent interactions make adherens junction-cytoskeletal linkage robust during morphogenesis. The Journal of Cell Biology. 220
Slep KC. (2020) Cytoskeletal Repair: Microtubule Orthopaedics to the Rescue. Current Biology : Cb. 30: R646-R649
Leano JB, Slep KC. (2019) Structures of TOG1 and TOG2 from the human microtubule dynamics regulator CLASP1. Plos One. 14: e0219823
Slep KC. (2019) Cytoskeletal cryptography: structure and mechanism of an eraser. Nature Structural & Molecular Biology. 26: 532-534
Chen Y, Wang P, Slep KC. (2018) Mapping multivalency in the CLIP-170-EB1 microtubule plus end complex. The Journal of Biological Chemistry
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