Catherine M. Eakin, Ph.D.

Affiliations: 
Yale University, New Haven, CT 
Area:
Protein Folding and Dynamics, Structural Biology
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"Catherine Eakin"
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Parents

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Andrew D. Miranker grad student 2005 Yale
 (Origins of transition metal mediated amyloidosis of Beta2-microglobulin.)
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Publications

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Calabrese MF, Eakin CM, Wang JM, et al. (2008) A regulatable switch mediates self-association in an immunoglobulin fold. Nature Structural & Molecular Biology. 15: 965-71
Heikaus CC, Stout JR, Sekharan MR, et al. (2008) Solution structure of the cGMP binding GAF domain from phosphodiesterase 5: insights into nucleotide specificity, dimerization, and cGMP-dependent conformational change. The Journal of Biological Chemistry. 283: 22749-59
Eakin CM, Berman AJ, Miranker AD. (2006) A native to amyloidogenic transition regulated by a backbone trigger. Nature Structural & Molecular Biology. 13: 202-8
Eakin CM, Miranker AD. (2005) From chance to frequent encounters: origins of beta2-microglobulin fibrillogenesis. Biochimica Et Biophysica Acta. 1753: 92-9
Eakin CM, Attenello FJ, Morgan CJ, et al. (2004) Oligomeric assembly of native-like precursors precedes amyloid formation by beta-2 microglobulin. Biochemistry. 43: 7808-15
Eakin CM, Knight JD, Morgan CJ, et al. (2002) Formation of a copper specific binding site in non-native states of beta-2-microglobulin. Biochemistry. 41: 10646-56
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