James A. Hebda, Ph.D.

Affiliations: 
Yale University, New Haven, CT 
Area:
Protein Folding and Dynamics, Structural Biology
Google:
"James Hebda"
Mean distance: 8.99
 

Parents

Sign in to add mentor
Andrew D. Miranker grad student 2011 Yale
 (Elucidating the Mechanism of Amyloid Assembly in Islet Amyloid Polypeptide Through Small Molecule Interference.)
Patricia O'Hara post-doc Amherst College
BETA: Related publications

Publications

You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Kumar S, Schlamadinger DE, Brown MA, et al. (2015) Islet amyloid-induced cell death and bilayer integrity loss share a molecular origin targetable with oligopyridylamide-based α-helical mimetics. Chemistry & Biology. 22: 369-78
Hebda JA, Magzoub M, Miranker AD. (2014) Small molecule screening in context: lipid-catalyzed amyloid formation. Protein Science : a Publication of the Protein Society. 23: 1341-8
Cabrejo R, Hebda J, O'Hara PB. (2014) Clarifying the Intersection Between Alpha-Crystallin B Function and Oligomerization by Altering Aggregation Conditions Biophysical Journal. 106: 471a
Schlamadinger DE, Kumar S, Magzoub M, et al. (2013) Inhibition and Mechanism of Islet Amyloid Polypeptide Toxicity Biophysical Journal. 104: 56a
Cheng KW, Cabrejo RG, Pearlman AH, et al. (2013) Clarifying Alpha Crystallin Chaperone Function by using an Insulin B-Chain Aggregation Model Biophysical Journal. 104: 48a
Hebda JA, Pearlman A, O'Hara PB. (2013) Characterizing the Role of Palindromic Strand Exchange in Alpha Crystallin Oligomerization Biophysical Journal. 104: 394a
Santos J, Cabrejo R, O'Hara P, et al. (2012) Elucidating Molecular Constraints that Effect Alpha Crystallin Oligomerization, Stability, and Chaperone Function Biophysical Journal. 102: 60a
Saraogi I, Hebda JA, Becerril J, et al. (2010) Synthetic alpha-helix mimetics as agonists and antagonists of islet amyloid polypeptide aggregation. Angewandte Chemie (International Ed. in English). 49: 736-9
Magzoub M, Hebda JA, Miranker A. (2010) Small Molecule Inhibitors of Islet Amyloid Polypeptide Fibrillogenesis and Cytotoxicity Biophysical Journal. 98: 255a
Hebda JA, Saraogi I, Magzoub M, et al. (2009) A peptidomimetic approach to targeting pre-amyloidogenic states in type II diabetes. Chemistry & Biology. 16: 943-50
See more...