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Kristen L. Johnson, Ph.D.

Affiliations: 
Columbia University, New York, NY 
Area:
gene regulation in the immune system
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"Kristen Johnson"
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Kathryn L. Calame grad student 2005 Columbia
 (The modulation of chromatin structure in the V(H) locus during lineage commitment and gene rearrangement.)

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Publications

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Wong JB, Hewitt SL, Heltemes-Harris LM, et al. (2019) B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage. Nature Communications. 10: 4768
Kerfoot SM, Yaari G, Patel JR, et al. (2011) Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone. Immunity. 34: 947-60
Johnson K, Reddy KL, Singh H. (2009) Molecular pathways and mechanisms regulating the recombination of immunoglobulin genes during B-lymphocyte development. Advances in Experimental Medicine and Biology. 650: 133-47
Johnson K, Hashimshony T, Sawai CM, et al. (2008) Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling. Immunity. 28: 335-45
Johnson K, Shapiro-Shelef M, Tunyaplin C, et al. (2005) Regulatory events in early and late B-cell differentiation. Molecular Immunology. 42: 749-761
Johnson K, Pflugh DL, Yu D, et al. (2004) B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5. Nature Immunology. 5: 853-61
Hsu LY, Liang HE, Johnson K, et al. (2004) Pax5 activates immunoglobulin heavy chain V to DJ rearrangement in transgenic thymocytes. The Journal of Experimental Medicine. 199: 825-30
Johnson K, Calame K. (2003) Transcription factors controlling the beginning and end of B-cell differentiation. Current Opinion in Genetics & Development. 13: 522-528
Johnson K, Angelin-Duclos C, Park S, et al. (2003) Changes in histone acetylation are associated with differences in accessibility of V(H) gene segments to V-DJ recombination during B-cell ontogeny and development. Molecular and Cellular Biology. 23: 2438-50
Angelin-Duclos C, Johnson K, Liao J, et al. (2003) An interfering form of Blimp-1 increases IgM secreting plasma cells and blocks maturation of peripheral B cells. European Journal of Immunology. 32: 3765-75
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