Luisa Cimmino, Ph.D.

Columbia University, New York, NY 
gene regulation in the immune system
"Luisa Cimmino"
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Kathryn L. Calame grad student 2007 Columbia
 (The role of Blimp-1 in T -lymphocyte homeostasis and function.)
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Inoue S, Li WY, Tseng A, et al. (2016) Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2. Cancer Cell
Gao J, Buckley SM, Cimmino L, et al. (2015) The CUL4-DDB1 ubiquitin ligase complex controls adult and embryonic stem cell differentiation and homeostasis. Elife. 4
Mullenders J, Aranda-Orgilles B, Lhoumaud P, et al. (2015) Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms. The Journal of Experimental Medicine
Shih AH, Jiang Y, Meydan C, et al. (2015) Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia. Cancer Cell. 27: 502-15
Cimmino L, Dawlaty MM, Ndiaye-Lobry D, et al. (2015) TET1 is a tumor suppressor of hematopoietic malignancy. Nature Immunology. 16: 653-62
Witkowski MT, Cimmino L, Hu Y, et al. (2015) Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia. Leukemia. 29: 1301-11
Hu W, Dooley J, Chung SS, et al. (2015) miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a. Blood. 125: 2206-16
Liu GJ, Cimmino L, Jude JG, et al. (2014) Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia. Genes & Development. 28: 1337-50
Schwickert TA, Tagoh H, Gültekin S, et al. (2014) Stage-specific control of early B cell development by the transcription factor Ikaros. Nature Immunology. 15: 283-93
Lobry C, Ntziachristos P, Ndiaye-Lobry D, et al. (2013) Notch pathway activation targets AML-initiating cell homeostasis and differentiation. The Journal of Experimental Medicine. 210: 301-19
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