James R. Fuchs, Ph.D.
|Pennsylvania State University, State College, PA, United States|
|2007-||Medicinal Chemistry and Pharmacognosy||Ohio State University, Columbus, Columbus, OH|
Area:Natural products synthesis
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|Patel PA, Kvaratskhelia N, Mansour Y, et al. (2016) Indole-based allosteric inhibitors of HIV-1 integrase. Bioorganic & Medicinal Chemistry Letters|
|Yan J, Wang Q, Zou K, et al. (2015) Inhibition of the JAK2/STAT3 signaling pathway exerts a therapeutic effect on osteosarcoma. Molecular Medicine Reports. 12: 498-502|
|Ren Y, Yuan C, Deng Y, et al. (2015) Cytotoxic and natural killer cell stimulatory constituents of Phyllanthus songboiensis. Phytochemistry. 111: 132-40|
|Luo S, Kang HS, Krunic A, et al. (2015) Trichormamides C and D, antiproliferative cyclic lipopeptides from the cultured freshwater cyanobacterium cf. Oscillatoria sp. UIC 10045 Bioorganic and Medicinal Chemistry|
|Luo S, Krunic A, Kang HS, et al. (2014) Trichormamides A and B with Antiproliferative Activity from the Cultured Freshwater Cyanobacterium Trichormus sp. UIC 10339. Journal of Natural Products|
|Fadel HJ, Morrison JH, Saenz DT, et al. (2014) TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism. Journal of Virology. 88: 9704-17|
|Ren Y, Lantvit DD, Deng Y, et al. (2014) Potent cytotoxic arylnaphthalene lignan lactones from Phyllanthus poilanei. Journal of Natural Products. 77: 1494-504|
|Kim TD, Fuchs JR, Schwartz E, et al. (2014) Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors. American Journal of Translational Research. 6: 236-47|
|Sharma A, Slaughter A, Jena N, et al. (2014) A new class of multimerization selective inhibitors of HIV-1 integrase. Plos Pathogens. 10: e1004171|
|Pan L, Woodard JL, Lucas DM, et al. (2014) Rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species. Natural Product Reports. 31: 924-39|