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Shannon C. Flagg, Ph.D.

Affiliations: 
Chemistry University of Massachusetts, Amherst, Amherst, MA 
Area:
Enzymology and Bio-Inorganic Chemistry Enzymology and Electronic Structure of Non-heme Fe, Hydrogen Tunneling Effects in Biological C-H Activation, Biomimetic Nanocluster Self-Assembly
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"Shannon Flagg"
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Parents

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Michael Knapp grad student 2011 U Mass Amherst
 (Selective inhibition and mechanistic studies of the human oxygen sensor, Prolyl Hydroxylase Domain 2 (PHD2).)

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Publications

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Flagg SC, Giri N, Pektas S, et al. (2012) Inverse solvent isotope effects demonstrate slow aquo release from hypoxia inducible factor-prolyl hydroxylase (PHD2). Biochemistry. 51: 6654-66
Flagg SC, Martin CB, Taabazuing CY, et al. (2012) Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH). Journal of Inorganic Biochemistry. 113: 25-30
Saban E, Flagg SC, Knapp MJ. (2011) Uncoupled O2-activation in the human HIF-asparaginyl hydroxylase, FIH, does not produce reactive oxygen species. Journal of Inorganic Biochemistry. 105: 630-6
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