Sylvie Beaubien, Ph.D.

Affiliations: 
Université de Sherbrooke, Sherbrooke, Québec, Canada 
Area:
Organic Chemistry
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"Sylvie Beaubien"
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Pierre Deslongchamps grad student 2003 Université de Sherbrooke
 (Synthese totale de 14beta-fluorosteroides via la reaction de Diels -Alder transannulaire.)
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Publications

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Hoveyda HR, Marsault E, Gagnon R, et al. (2011) Optimization of the potency and pharmacokinetic properties of a macrocyclic ghrelin receptor agonist (Part I): Development of ulimorelin (TZP-101) from hit to clinic. Journal of Medicinal Chemistry. 54: 8305-20
Marsault E, Hoveyda HR, Peterson ML, et al. (2009) High throughput solid phase parallel synthesis of macrocyclic peptidomimetics. Advances in Experimental Medicine and Biology. 611: 15-6
Beaubien S, Hoveyda HR, Vézina M, et al. (2009) Parallel solid-phase synthesis of macrocyclic peptidomimetics using Ru-catalyzed ring-closing metathesis and a new application of cross metathesis. Advances in Experimental Medicine and Biology. 611: 13-4
Marsault E, Hoveyda HR, Gagnon R, et al. (2008) Efficient parallel synthesis of macrocyclic peptidomimetics. Bioorganic & Medicinal Chemistry Letters. 18: 4731-5
Marsault E, Benakli K, Beaubien S, et al. (2007) Potent macrocyclic antagonists to the motilin receptor presenting novel unnatural amino acids. Bioorganic & Medicinal Chemistry Letters. 17: 4187-90
Marsault E, Hoveyda HR, Peterson ML, et al. (2006) Discovery of a new class of macrocyclic antagonists to the human motilin receptor. Journal of Medicinal Chemistry. 49: 7190-7
Beaubien S, Deslongchamps P. (2006) Total synthesis of 14β-fluorosteroids via a transannular Diels-Alder reaction Canadian Journal of Chemistry. 84: 29-48
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