Nicholas A. Pierson, Ph.D.

Affiliations: 
Chemistry Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Structure analysis of biological systems using mass spectrometry-based techniques
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"Nicholas Pierson"
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David Clemmer grad student 2013 Indiana University
 (Understanding peptide structure through studies of the model system bradykinin: From solution to the gas phase.)
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Publications

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Blincoe WD, Rodriguez-Granillo A, Saurí J, et al. (2018) Identification of ortho-Substituted Benzoic Acid/Ester Derivatives via the Gas-Phase Neighboring Group Participation Effect in (+)-ESI High Resolution Mass Spectrometry. Journal of the American Society For Mass Spectrometry
Pierson NA, Makarov AA, Strulson CA, et al. (2017) Semi-automated screen for global protein conformational changes in solution by IMS-MS combined with size-exclusion chromatography and differential hydrogen-deuterium exchange. Journal of Chromatography. A
Fuller DR, Glover MS, Pierson NA, et al. (2016) Cis→Trans Isomerization of Pro(7) in Oxytocin Regulates Zn(2+) Binding. Journal of the American Society For Mass Spectrometry
Pierson NA, Clemmer DE. (2015) An IMS-IMS threshold method for semi-quantitative determination of activation barriers: Interconversion of proline cis↔trans forms in triply protonated bradykinin. International Journal of Mass Spectrometry. 377: 646-654
Fort KL, Silveira JA, Pierson NA, et al. (2014) From solution to the gas phase: factors that influence kinetic trapping of substance P in the gas phase. The Journal of Physical Chemistry. B. 118: 14336-44
Wyttenbach T, Pierson NA, Clemmer DE, et al. (2014) Ion mobility analysis of molecular dynamics. Annual Review of Physical Chemistry. 65: 175-96
Silveira JA, Fort KL, Kim D, et al. (2013) From solution to the gas phase: stepwise dehydration and kinetic trapping of substance P reveals the origin of peptide conformations. Journal of the American Chemical Society. 135: 19147-53
Pierson NA, Chen L, Russell DH, et al. (2013) Cis-trans isomerizations of proline residues are key to bradykinin conformations. Journal of the American Chemical Society. 135: 3186-92
Shi H, Pierson NA, Valentine SJ, et al. (2012) Conformation types of ubiquitin [M+8H]8+ Ions from water:methanol solutions: evidence for the N and A States in aqueous solution. The Journal of Physical Chemistry. B. 116: 3344-52
Jung JE, Pierson NA, Marquardt A, et al. (2011) Differentiation of compact and extended conformations of di-ubiquitin conjugates with lysine-specific isopeptide linkages by ion mobility-mass spectrometry. Journal of the American Society For Mass Spectrometry. 22: 1463-71
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