Franz Gruswitz, Ph.D.

x-ray crystallography, ncRNA structure, APOBEC3G

Joseph E. Wedekind	grad student	2006	Rochester
(Folding studies of outer surface protein A fragments from Borrellia burgdorferi: A model beta-sheet, and, Structural investigation of the catalytic doman of human type II inosine 5'-monophosphate dehydrogenase.)

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Chaudhary S, Pak JE, Gruswitz F, et al. (2012) Overexpressing human membrane proteins in stably transfected and clonal human embryonic kidney 293S cells Nature Protocols. 7: 453-466
Gruswitz F, Chaudhary S, Ho JD, et al. (2010) Function of human Rh based on structure of RhCG at 2.1 A. Proceedings of the National Academy of Sciences of the United States of America. 107: 9638-43
Newby ZE, O'Connell JD, Gruswitz F, et al. (2009) A general protocol for the crystallization of membrane proteins for X-ray structural investigation. Nature Protocols. 4: 619-37
Hays FA, Roe-Zurz Z, Li M, et al. (2009) Ratiocinative screen of eukaryotic integral membrane protein expression and solubilization for structure determination. Journal of Structural and Functional Genomics. 10: 9-16
Gruswitz F, O'Connell J, Stroud RM. (2007) Inhibitory complex of the transmembrane ammonia channel, AmtB, and the cytosolic regulatory protein, GlnK, at 1.96 A. Proceedings of the National Academy of Sciences of the United States of America. 104: 42-7
Gruswitz F, Frishman M, Goldstein BM, et al. (2005) Coupling of MBP fusion protein cleavage with sparse matrix crystallization screens to overcome problematic protein solubility. Biotechniques. 39: 476, 478, 480