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Jenna F. DuMond, Ph.D.

Affiliations: 
Chemistry Wake Forest University, Winston-Salem, NC, United States 
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"Jenna DuMond"
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S. Bruce King grad student 2012 Wake Forest
 (Acyloxy nitroso compounds as nitroxyl donors and their interactions with heme and thiol proteins.)

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Werner-Allen JW, Monti S, DuMond JF, et al. (2018) Isoindole linkages provide a pathway for DOPAL-mediated crosslinking of α-synuclein. Biochemistry
Werner-Allen JW, DuMond JF, Levine RL, et al. (2016) Toxic Dopamine Metabolite DOPAL Forms an Unexpected Dicatechol Pyrrole Adduct with Lysines of α-Synuclein. Angewandte Chemie (International Ed. in English). 55: 7374-8
Cortese-Krott MM, Kuhnle GG, Dyson A, et al. (2015) Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl. Proceedings of the National Academy of Sciences of the United States of America
Mitroka S, Shoman ME, DuMond JF, et al. (2013) Direct and nitroxyl (HNO)-mediated reactions of acyloxy nitroso compounds with the thiol-containing proteins glyceraldehyde 3-phosphate dehydrogenase and alkyl hydroperoxide reductase subunit C. Journal of Medicinal Chemistry. 56: 6583-92
Bellavia L, DuMond JF, Perlegas A, et al. (2013) Nitroxyl accelerates the oxidation of oxyhemoglobin by nitrite. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 31: 38-47
Donzelli S, Fischer G, King BS, et al. (2013) Pharmacological characterization of 1-nitrosocyclohexyl acetate, a long-acting nitroxyl donor that shows vasorelaxant and antiaggregatory effects. The Journal of Pharmacology and Experimental Therapeutics. 344: 339-47
DuMond JF, Wright MW, King SB. (2013) Water soluble acyloxy nitroso compounds: HNO release and reactions with heme and thiol containing proteins. Journal of Inorganic Biochemistry. 118: 140-7
Bellavia L, Dumond JF, Perlegas A, et al. (2013) P26 Nitric Oxide. 31: S24
Huang Z, Kaur J, Bhardwaj A, et al. (2012) O2-sulfonylethyl protected isopropylamine diazen-1-ium-1,2-diolates as nitroxyl (HNO) donors: synthesis, β-elimination fragmentation, HNO release, positive inotropic properties, and blood pressure lowering studies. Journal of Medicinal Chemistry. 55: 10262-71
Gao WD, Murray CI, Tian Y, et al. (2012) Nitroxyl-mediated disulfide bond formation between cardiac myofilament cysteines enhances contractile function. Circulation Research. 111: 1002-11
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