Philip D. Mosier, Ph.D.

Affiliations: 
Pennsylvania State University, State College, PA, United States 
Area:
Computational Chemistry
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"Philip Mosier"
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Parents

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Peter C. Jurs grad student 2003 Penn State
 (Prediction of chemical properties and biological activities of organic compounds from molecular structure and use of probabilistic and generalized regression neural networks.)
Umesh R. Desai post-doc 2009-2011 VCU
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Publications

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Niso M, Mosier PD, Marottoli R, et al. (2019) High-affinity sigma-1 (σ) receptor ligands based on the σ antagonist PB212. Future Medicinal Chemistry. 11: 2547-2562
Abdelkhalek AS, Alley GS, Alwassil OI, et al. (2018) "Methylene Bridge" to 5-HT3 Receptor Antagonists: Conformationally-Constrained Phenylguanidines". Acs Chemical Neuroscience
Etobayeva I, Linden SB, Alem F, et al. (2018) Discovery and Biochemical Characterization of PlyP56, PlyN74, and PlyTB40- Specific Endolysins. Viruses. 10
Che T, Majumdar S, Zaidi SA, et al. (2018) Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor. Cell
Chiang MJ, Musayev FN, Kosikova M, et al. (2017) Maintaining pH-dependent conformational flexibility of M1 is critical for efficient influenza A virus replication. Emerging Microbes & Infections. 6: e108
Sankarayanarayanan NV, Strebel TR, Boothello RS, et al. (2017) A Hexasaccharide Containing Rare 2-O-Sulfate-Glucuronic Acid Residues Selectively Activates Heparin Cofactor II. Angewandte Chemie (International Ed. in English)
Mosier PD, Chiang MJ, Lin Z, et al. (2016) Broad Spectrum Anti-Influenza Agents by Inhibiting Self-Association of Matrix Protein 1. Scientific Reports. 6: 32340
Sarkar A, Yu W, Desai UR, et al. (2016) Estimating glycosaminoglycan-protein interaction affinity: Water dominates the specific antithrombin-heparin interaction. Glycobiology
Joseph PR, Mosier PD, Desai UR, et al. (2015) Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions. The Biochemical Journal. 472: 121-33
Vardy E, Sassano MF, Rennekamp AJ, et al. (2015) Single Amino Acid Variation Underlies Species-Specific Sensitivity to Amphibian Skin-Derived Opioid-like Peptides. Chemistry & Biology. 22: 764-75
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