Steven J. Metallo
Affiliations: | 2001- | Chemistry | Georgetown University, Washington, DC |
Area:
chemical biology, biophysical chemistry, and surface chemistryWebsite:
https://chemistry.georgetown.edu/MetalloGoogle:
"Steven Joseph Metallo"Bio:
https://softmatter.georgetown.edu/people/metallo
http://www.researchgate.net/profile/Steven_Metallo
Mean distance: 6.53 | S | N | B | C | P |
Parents
Sign in to add mentor| Alanna Schepartz | grad student | 1999 | Yale | |
| (Mechanism and specificity of dimeric transcription factors) | ||||
| George M. Whitesides | post-doc | 1998-2001 | Harvard | |
| (multivalency and surface chemistry) | ||||
Children
Sign in to add trainee| Sarai Obando | grad student | 2008 | Georgetown |
| Dalia Issa Hammoudeh | grad student | 2009 | Georgetown |
| Ariele Giorgio Viacava Follis | grad student | 2009 | Georgetown |
| Jerez A. Te | grad student | 2010 | Georgetown |
| Anthony D. Kammerich | grad student | 2011 | Georgetown |
| Alison Mae Reed | grad student | 2011 | Georgetown |
| David A. Gaviria | grad student | 2013 | Georgetown |
| Lisette M. Fred | grad student | 2009-2016 | Georgetown |
| Kaitlyn P. Gerhart | grad student | 2009-2016 | Georgetown |
| Veselin Svetoslavov Dobrev | grad student | 2010-2018 | Georgetown |
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Publications
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| Jaiprashad R, De Silva SR, Fred Lucena LM, et al. (2022) Portability of a Small-Molecule Binding Site between Disordered Proteins. Biomolecules. 12 |
| Meyer E, DeSilva SR, Metallo SJ. (2022) Portability of Small Molecule Binding Sites in Intrinsically Disordered Proteins. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology |
| Dobrev VS, Fred LM, Gerhart KP, et al. (2018) Characterization of the Binding of Small Molecules to Intrinsically Disordered Proteins. Methods in Enzymology. 611: 677-702 |
| Tsafou K, Tiwari PB, Forman-Kay JD, et al. (2018) Targeting intrinsically disordered transcription factors: Changing the paradigm. Journal of Molecular Biology |
| Gerhart KP, Metallo SJ. (2015) Interaction of the Intrinsically Disordered c-Myc Oncoprotein with Racemic and Enantiopure Small Molecules Biophysical Journal. 108: 389a |
| Fred LM, Gerhart KP, Zablotsky BL, et al. (2015) Primary Sequence Controls the Specificity and Affinity of a Small Molecule Binding to the Intrinsically Disordered Protein c-Myc Biophysical Journal. 108: 389a |
| Uversky VN, Davé V, Iakoucheva LM, et al. (2014) Pathological unfoldomics of uncontrolled chaos: Intrinsically disordered proteins and human diseases Chemical Reviews. 114: 6844-6879 |
| Gerhart KP, Metallo SJ. (2014) Enantiospecific Recognition of the Intrinsically Disordered C-Myc Oncoprotein by Small Molecules Biophysical Journal. 106: 687a |
| Guo J, Clausen DM, Prochownik EV, et al. (2013) Abstract 1019: Cytotoxicityin vitro, pharmacokinetics and tissue distribution of Link-N3 and Link-F3, two bivalent small molecules inhibitors of c-Myc/Max interactions in C.B-17 SCID mice bearing Daudi Burkitt's lymphoma xenografts. Cancer Research. 73: 1019-1019 |
| Fred LM, Gerhart KP, Zablotsky BL, et al. (2013) Hydrophobic and Hydrophilic Residues are Important for Small Molecule Binding to the Intrinsically Disordered Protein c-Myc Biophysical Journal. 104: 52a-53a |