Cyrus Michael Ghajar

Affiliations: 
Fred Hutchinson Cancer Research Center, Seattle, WA, United States 
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"Cyrus Ghajar"
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SNBCP

Parents

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Andrew James Putnam grad student 2003-2008 UC Irvine
 (The contributions of matrix density and interstitial cell-mediated proteolysis to capillary morphogenesis and tumor invasion.)

Children

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Bianca H. Dang research assistant 2015-2016 Fred Hutchinson Cancer Center (Neurotree)
Erica T. Goddard post-doc Fred Hutchinson Cancer Center (Cell Biology Tree)
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Publications

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Grzelak CA, Goddard ET, Lederer EE, et al. (2021) Elimination of fluorescent protein immunogenicity permits modeling of metastasis in immune-competent settings. Cancer Cell
Lim AR, Ghajar CM. (2021) Thorny ground, rocky soil: tissue-specific mechanisms of tumor dormancy and relapse. Seminars in Cancer Biology
Carlson P, Dasgupta A, Grzelak CA, et al. (2019) Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy. Nature Cell Biology
Goddard ET, Bozic I, Riddell SR, et al. (2018) Dormant tumour cells, their niches and the influence of immunity. Nature Cell Biology. 20: 1240-1249
Dasgupta A, Lim AR, Ghajar CM. (2017) Circulating and disseminated tumor cells: harbingers or initiators of metastasis? Molecular Oncology. 11: 40-61
Ghajar CM, Peinado H, Mori H, et al. (2013) The perivascular niche regulates breast tumour dormancy. Nature Cell Biology. 15: 807-17
Ghosh S, Ashcraft K, Jahid MJ, et al. (2013) Regulation of adipose oestrogen output by mechanical stress. Nature Communications. 4: 1821
Mori H, Lo AT, Inman JL, et al. (2013) Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1. Development (Cambridge, England). 140: 343-52
Bissell MJ, Ghajar CM, Lee LP. (2012) From single cells to biology. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 357-9
Alcaraz J, Mori H, Ghajar CM, et al. (2011) Collective epithelial cell invasion overcomes mechanical barriers of collagenous extracellular matrix by a narrow tube-like geometry and MMP14-dependent local softening. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 1153-66
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