Xue Ge, Ph.D.

Affiliations: 
University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Studies on novel enzyme mechanisms; epimerases and racemases; sugar nucleotide-modifying enzymes; isotope effects; inhibitor design; site-directed mutagenesis
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"Xue Ge"
Mean distance: 8.38
 
SNBCP

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Martin E. Tanner grad student 2000 UBC
 (Covalent catalysis in the UDP-glucose dehydrogenase reaction.)
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Publications

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Ge X, Penney LC, Van De Rijn I, et al. (2004) Active site residues and mechanism of UDP-glucose dehydrogenase European Journal of Biochemistry. 271: 14-22
Ge X, Sirich TL, Beyer MK, et al. (2001) A strategy for the determination of enzyme kinetics using electrospray ionization with an ion trap mass spectrometer. Analytical Chemistry. 73: 5078-82
Armstrong JI, Ge X, Verdugo DE, et al. (2001) A library approach to the generation of bisubstrate analogue sulfotransferase inhibitors. Organic Letters. 3: 2657-60
Verdugo DE, Cancilla MT, Ge X, et al. (2001) Discovery of estrogen sulfotransferase inhibitors from a purine library screen. Journal of Medicinal Chemistry. 44: 2683-6
Ge X, Campbell RE, Van de Rijn I, et al. (1998) Covalent adduct formation with a mutated enzyme: Evidence for a thioester intermediate in the reaction catalyzed by UDP-glucose dehydrogenase Journal of the American Chemical Society. 120: 6613-6614
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