Wade C. Winkler, Ph.D.

Affiliations: 
Ohio State University, Columbus, Columbus, OH 
Area:
Regulation of gene expression
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"Wade Winkler"
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SNBCP

Parents

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Ronald R. Breaker grad student
Tina M. Henkin grad student 2002 Ohio State
 (RNA elements required for T box antitermination.)

Children

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Irnov Irnov grad student UT Southwestern
Catherine Wakeman grad student 2009 UT Southwestern (Microtree)
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Publications

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Kim SK, Orr MW, Turdiev H, et al. (2024) Diribonuclease activity eliminates toxic diribonucleotide accumulation. Cell Reports. 43: 114759
Elghondakly A, Jermain MD, Winkler WC, et al. (2024) Major-groove sequence-specific RNA recognition by LoaP, a paralog of transcription elongation factor NusG. Structure (London, England : 1993)
Myers TM, Ingle S, Weiss CA, et al. (2023) Bacillus subtilis NrnB is expressed during sporulation and acts as a unique 3'-5' exonuclease. Nucleic Acids Research
Weiss CA, Myers TM, Wu CH, et al. (2022) NrnA is a 5'-3' exonuclease that processes short RNA substrates in vivo and in vitro. Nucleic Acids Research
Lee VT, Sondermann H, Winkler W. (2022) Nano-RNases: oligo- or dinucleases? Fems Microbiology Reviews
Kim SK, Lormand JD, Weiss CA, et al. (2022) Correction: A dedicated diribonuclease resolves a key bottleneck for the terminal step of RNA degradation. Elife. 11
Papenfort K, Woodson SA, Schmitz RA, et al. (2022) Special Issue: Regulating with RNA in Microbes: In conjunction with the 6th Meeting on Regulating with RNA in Bacteria and Archaea. Molecular Microbiology. 117: 1-3
Lormand JD, Kim SK, Walters-Marrah GA, et al. (2021) Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife. 10
Elghondakly A, Hao Wu C, Klupt S, et al. (2021) A NusG Specialized Paralog That Exhibits Specific, High-Affinity RNA-Binding Activity. Journal of Molecular Biology. 167100
Weiss CA, Winkler WC. (2021) Riboswitch-Mediated Detection of Metabolite Fluctuations During Live Cell Imaging of Bacteria. Methods in Molecular Biology (Clifton, N.J.). 2323: 153-170
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