Heather M. Bigott, Ph.D.

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Radiopharmaceutical Development
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SNBCP

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Michael J. Welch grad student 2004 Washington University
 (Production of technetium -94m and the synthesis, characterization and evaluation of technetium -94m radiopharmaceuticals.)
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Publications

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Bigott HM, Laforest R, Liu X, et al. (2006) Advances in the production, processing and microPET image quality of technetium-94m. Nuclear Medicine and Biology. 33: 923-33
Myerson RJ, Singh AK, Bigott HM, et al. (2006) Monitoring the effect of mild hyperthermia on tumour hypoxia by Cu-ATSM PET scanning. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 22: 93-115
Bigott HM, Prior JL, Piwnica-Worms DR, et al. (2005) Imaging multidrug resistance P-glycoprotein transport function using microPET with technetium-94m-sestamibi. Molecular Imaging. 4: 30-9
Bigott HM, Parent E, Luyt LG, et al. (2005) Design and synthesis of functionalized cyclopentadienyl tricarbonylmetal complexes for technetium-94m PET imaging of estrogen receptors. Bioconjugate Chemistry. 16: 255-64
Luyt LG, Bigott HM, Welch MJ, et al. (2003) 7alpha- and 17alpha-substituted estrogens containing tridentate tricarbonyl rhenium/technetium complexes: synthesis of estrogen receptor imaging agents and evaluation using microPET with technetium-94m. Bioorganic & Medicinal Chemistry. 11: 4977-89
Rogers BE, Bigott HM, McCarthy DW, et al. (2003) MicroPET imaging of a gastrin-releasing peptide receptor-positive tumor in a mouse model of human prostate cancer using a 64Cu-labeled bombesin analogue. Bioconjugate Chemistry. 14: 756-63
Bigott HM, Mccarthy DW, Wüst FR, et al. (2001) Production, processing and uses of 94mTc Journal of Labelled Compounds and Radiopharmaceuticals. 44: S119-S121
Mccarthy DW, Bigott HM, Perkins TA, et al. (2001) A research resource in radionuclide research Journal of Labelled Compounds and Radiopharmaceuticals. 44: S817-S819
Luyt LG, Mull ES, Katzenellenbogen JA, et al. (2001) Preparation of cyclopentadienyl tricarbonyl technetium-94m complexes Journal of Labelled Compounds and Radiopharmaceuticals. 44: S489-S490
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