Ping-Chuan Tsai, Ph.D.

Affiliations: 
Texas A & M University, College Station, TX, United States 
Area:
Enzymology
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"Ping-Chuan Tsai"
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Frank M. Raushel grad student 2009 Texas A & M
 (Directed evolution of phosphotriesterase for stereoselective detoxification of organophosphate nerve agents.)
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Tsai PC, Fox N, Bigley AN, et al. (2012) Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents. Biochemistry. 51: 6463-75
Tsai PC, Bigley A, Li Y, et al. (2010) Stereoselective hydrolysis of organophosphate nerve agents by the bacterial phosphotriesterase. Biochemistry. 49: 7978-87
Tsai PC, Fan Y, Kim J, et al. (2010) Structural determinants for the stereoselective hydrolysis of chiral substrates by phosphotriesterase. Biochemistry. 49: 7988-97
Kim J, Tsai PC, Chen SL, et al. (2008) Structure of diethyl phosphate bound to the binuclear metal center of phosphotriesterase. Biochemistry. 47: 9497-504
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