Nitish Agrawal, Ph.D.

Enzyme Catalysis

Amnon Kohen	grad student	2005	University of Iowa
(Mechanistic investigations of classical and flavin-dependent thymidylate synthases.)

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Mason A, Agrawal N, Washington MT, et al. (2006) A lag-phase in the reduction of flavin dependent thymidylate synthase (FDTS) revealed a mechanistic missing link. Chemical Communications (Cambridge, England). 1781-3
Agrawal N, Lesley SA, Kuhn P, et al. (2004) Mechanistic studies of a flavin-dependent thymidylate synthase. Biochemistry. 43: 10295-301
Agrawal N, Mihai C, Kohen A. (2004) Microscale synthesis of isotopically labeled R-[6-xH]N5,N10-methylene-5,6,7,8-tetrahydrofolate as a cofactor for thymidylate synthase. Analytical Biochemistry. 328: 44-50
Agrawal N, Hong B, Mihai C, et al. (2004) Vibrationally enhanced hydrogen tunneling in the Escherichia coli thymidylate synthase catalyzed reaction. Biochemistry. 43: 1998-2006
Agrawal N, Kohen A. (2003) Microscale synthesis of 2-tritiated isopropanol and 4R-tritiated reduced nicotinamide adenine dinucleotide phosphate. Analytical Biochemistry. 322: 179-84