Huatao Guo, Ph.D.

Affiliations: 
University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
intron splicing
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Parents

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Alan M. Lambowitz grad student 2000 UT Austin
 (The target -site recognition mechanism of group II intron endonucleases and its use in gene targeting.)
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Publications

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Guo H, Arambula D, Ghosh P, et al. (2014) Diversity-generating Retroelements in Phage and Bacterial Genomes. Microbiology Spectrum. 2
Arambula D, Wong W, Medhekar BA, et al. (2013) Surface display of a massively variable lipoprotein by a Legionella diversity-generating retroelement. Proceedings of the National Academy of Sciences of the United States of America. 110: 8212-7
Guo H, Tse LV, Nieh AW, et al. (2011) Target site recognition by a diversity-generating retroelement. Plos Genetics. 7: e1002414
Guo H, Tse LV, Barbalat R, et al. (2008) Diversity-generating retroelement homing regenerates target sequences for repeated rounds of codon rewriting and protein diversification. Molecular Cell. 31: 813-23
Karberg M, Guo H, Zhong J, et al. (2001) Group II introns as controllable gene targeting vectors for genetic manipulation of bacteria Nature Biotechnology. 19: 1162-1167
Guo H, Karberg M, Long M, et al. (2000) Group II introns designed to insert into therapeutically relevant DNA target sites in human cells. Science (New York, N.Y.). 289: 452-7
Guo H, Zimmerly S, Perlman PS, et al. (1997) Group II intron endonucleases use both RNA and protein subunits for recognition of specific sequences in double-stranded DNA Embo Journal. 16: 6835-6848
Zimmerly S, Guo H, Perlman PS, et al. (1995) Group II intron mobility occurs by target DNA-primed reverse transcription. Cell. 82: 545-54
Zimmerly S, Guo H, Eskes R, et al. (1995) A group II intron RNA is a catalytic component of a DNA endonuclease involved in intron mobility. Cell. 83: 529-38
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