Sean D. Stowe, Ph.D.

Biochemistry|Functional Genomics North Carolina State University, Raleigh, NC 
"Sean Stowe"
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John Cavanagh grad student 2013 NCSU
 (Determination of the Cellular Effects of Antibiofilm Therapeutics and the Characterization of Potential Cellular Targets in Bacteria.)
David J. Weber post-doc 2013-2016 University of Maryland Medical School
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Milton ME, Draughn GL, Bobay BG, et al. (2019) The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis. Journal of Molecular Biology
Stowe SD, Thompson RJ, Peng L, et al. (2015) Membrane-permeabilizing activity of reverse-amide 2-aminoimidazole antibiofilm agents against Acinetobacter baumannii. Current Drug Delivery. 12: 223-30
Stowe SD, Olson AL, Losick R, et al. (2014) Chemical shift assignments and secondary structure prediction of the master biofilm regulator, SinR, from Bacillus subtilis. Biomolecular Nmr Assignments. 8: 155-8
Thompson RJ, Bobay BG, Stowe SD, et al. (2012) Identification of BfmR, a response regulator involved in biofilm development, as a target for a 2-Aminoimidazole-based antibiofilm agent. Biochemistry. 51: 9776-8
Stowe SD, Tucker AT, Thompson R, et al. (2012) Evaluation of the toxicity of 2-aminoimidazole antibiofilm agents using both cellular and model organism systems. Drug and Chemical Toxicology. 35: 310-5
Stowe SD, Richards JJ, Tucker AT, et al. (2011) Anti-biofilm compounds derived from marine sponges. Marine Drugs. 9: 2010-35
Richards JJ, Reyes S, Stowe SD, et al. (2009) Amide isosteres of oroidin: assessment of antibiofilm activity and C. elegans toxicity. Journal of Medicinal Chemistry. 52: 4582-5
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