Christine S. Cheng, Ph.D.

Affiliations: 
Bioinformatics University of California, San Diego, La Jolla, CA 
Area:
signaling, transcription, computational network; stress and immune responses, apoptosis, proliferation
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"Christine Cheng"
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SNBCP

Parents

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Alexander Hoffmann grad student 2011 UCSD
 (Innate immune gene expression programs defined by both regulated mRNA synthesis and decay.)
Aviv Regev post-doc MIT / Harvard (Management Information Systems Tree)
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Publications

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Mota A, Waxman HK, Hong R, et al. (2021) FOXR1 regulates stress response pathways and is necessary for proper brain development. Plos Genetics. 17: e1009854
Gate RE, Cheng CS, Aiden AP, et al. (2018) Genetic determinants of co-accessible chromatin regions in activated T cells across humans. Nature Genetics
Ji Z, He L, Rotem A, et al. (2018) Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation. Nature Communications. 9: 2068
Soto-Feliciano YM, Bartlebaugh JME, Liu Y, et al. (2017) PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes. Genes & Development
Fiziev P, Akdemir KC, Miller JP, et al. (2017) Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression. Cell Reports. 19: 875-889
Cheng CS, Behar MS, Suryawanshi GW, et al. (2017) Iterative Modeling Reveals Evidence of Sequential Transcriptional Control Mechanisms. Cell Systems
Sanjana NE, Wright J, Zheng K, et al. (2016) High-resolution interrogation of functional elements in the noncoding genome. Science (New York, N.Y.). 353: 1545-1549
Cheng CS, Rai K, Garber M, et al. (2013) Semiconductor-based DNA sequencing of histone modification states. Nature Communications. 4: 2672
Garber M, Yosef N, Goren A, et al. (2012) A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals. Molecular Cell. 47: 810-22
Escoubet-Lozach L, Benner C, Kaikkonen MU, et al. (2011) Mechanisms establishing TLR4-responsive activation states of inflammatory response genes. Plos Genetics. 7: e1002401
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