Andrew B. Caldwell, Ph.D.

Affiliations: 
Bioengineering University of California, San Diego, La Jolla, CA 
Area:
Alzheimer's disease; dementia; multi-omics; transcription, computational network; signaling; stress and immune responses
Website:
https://andrewbcaldwell.com
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"Andrew Caldwell"
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SNBCP

Parents

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Alexander Hoffmann grad student 2014 UCSD
 (Towards a Quantitative Understanding of TNF's Signaling Functions.)
Shankar Subramaniam post-doc 2014- UCSD (Biomechanics Tree)
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Publications

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Valdes P, Henry KW, Fitzgerald MQ, et al. (2023) Limitations of the human iPSC-derived neuron model for early-onset Alzheimer's disease. Molecular Brain. 16: 75
Patel AO, Caldwell AB, Ramachandran S, et al. (2023) Endotype Characterization Reveals Mechanistic Differences Across Brain Regions in Sporadic Alzheimer's Disease. Journal of Alzheimer's Disease Reports. 7: 957-972
Dwivedi I, Caldwell AB, Zhou D, et al. (2023) Methadone alters transcriptional programs associated with synapse formation in human cortical organoids. Translational Psychiatry. 13: 151
Caldwell AB, Anantharaman BG, Ramachandran S, et al. (2022) Transcriptomic profiling of sporadic Alzheimer's disease patients. Molecular Brain. 15: 83
Azad P, Caldwell AB, Ramachandran S, et al. (2022) ARID1B, a molecular suppressor of erythropoiesis, is essential for the prevention of Monge's disease. Experimental & Molecular Medicine
Caldwell AB, Liu Q, Zhang C, et al. (2022) Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Caldwell AB, Liu Q, Schroth GP, et al. (2020) Dedifferentiation and neuronal repression define familial Alzheimer's disease. Science Advances. 6
Subramaniam S, Caldwell A, Bhargava V, et al. (2018) Mechanisms Defining the Neuronal State Space Biophysical Journal. 114: 23a-24a
Caldwell AB, Cheng Z, Vargas JD, et al. (2014) Network dynamics determine the autocrine and paracrine signaling functions of TNF. Genes & Development. 28: 2120-33
Shih VF, Tsui R, Caldwell A, et al. (2011) A single NFκB system for both canonical and non-canonical signaling. Cell Research. 21: 86-102
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