Nishant Bhasin, Ph.D.

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
cell biophysics and polymer engineering
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"Nishant Bhasin"
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Dennis E. Discher grad student 2006 Penn
 (Single molecule structural studies of bridges, linkers, and hinges in multi-domain proteins: Natural variants, pathological mutants, and therapeutic designs.)
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Publications

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Krieger CC, Bhasin N, Tewari M, et al. (2010) Exon-skipped dystrophins for treatment of Duchenne muscular dystrophy: mass spectrometry mapping of most exons and cooperative domain designs based on single molecule mechanics. Cytoskeleton (Hoboken, N.J.). 67: 796-807
Johnson CP, Gaetani M, Ortiz V, et al. (2007) Pathogenic proline mutation in the linker between spectrin repeats: disease caused by spectrin unfolding. Blood. 109: 3538-43
Discher DE, Bhasin N, Johnson CP. (2006) Covalent chemistry on distended proteins. Proceedings of the National Academy of Sciences of the United States of America. 103: 7533-4
An X, Guo X, Zhang X, et al. (2006) Conformational stabilities of the structural repeats of erythroid spectrin and their functional implications. The Journal of Biological Chemistry. 281: 10527-32
Geng Y, Ahmed F, Bhasin N, et al. (2005) Visualizing worm micelle dynamics and phase transitions of a charged diblock copolymer in water. The Journal of Physical Chemistry. B. 109: 3772-9
Bhasin N, Law R, Liao G, et al. (2005) Molecular extensibility of mini-dystrophins and a dystrophin rod construct. Journal of Molecular Biology. 352: 795-806
Bhasin N, Johnson C, Sen S, et al. (2005) Interface concentration dependence in unfolding proteins using AFM Aiche Annual Meeting, Conference Proceedings. 1307-1311
Bhasin N, Carl P, Harper S, et al. (2004) Chemistry on a single protein, vascular cell adhesion molecule-1, during forced unfolding. The Journal of Biological Chemistry. 279: 45865-74
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