Adam J. Engler, Ph.D.

University of Pennsylvania, Philadelphia, PA, United States 
cell biophysics and polymer engineering
"Adam Engler"
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Dennis E. Discher grad student 2006 Penn
 (Mechanochemical signaling directs cell state: A mechanics of materials foundation for cell biology.)


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Andrew W. Holle grad student 2008-2013 UCSD
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Engler AJ, Discher DE. (2018) Rationally engineered advances in cancer research. Apl Bioengineering. 2: 031601
Hadden WJ, Young JL, Holle AW, et al. (2017) Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels. Proceedings of the National Academy of Sciences of the United States of America
Holle AW, McIntyre AJ, Kehe J, et al. (2016) High content image analysis of focal adhesion-dependent mechanosensitive stem cell differentiation. Integrative Biology : Quantitative Biosciences From Nano to Macro. 8: 1049-1058
Thomas KA, Gibbons MC, Lane JG, et al. (2016) Rotator cuff tear state modulates self-renewal and differentiation capacity of human skeletal muscle progenitor cells. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Zhang ZN, Freitas BC, Qian H, et al. (2016) Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction. Proceedings of the National Academy of Sciences of the United States of America
Happe CL, Engler AJ. (2016) Mechanical Forces Reshape Differentiation Cues That Guide Cardiomyogenesis. Circulation Research. 118: 296-310
Ondeck M, Engler A. (2016) Mechanical Characterization of a Dynamic and Tunable Methacrylated Hyaluronic Acid Hydrogel. Journal of Biomechanical Engineering
Wu H, Lee J, Vincent LG, et al. (2015) Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy. Cell Stem Cell. 17: 89-100
Meyer GA, Gibbons MC, Sato E, et al. (2015) Epimuscular Fat in the Human Rotator Cuff Is a Novel Beige Depot. Stem Cells Translational Medicine. 4: 764-74
Jun I, Lee YB, Choi YS, et al. (2015) Transfer stamping of human mesenchymal stem cell patches using thermally expandable hydrogels with tunable cell-adhesive properties. Biomaterials. 54: 44-54
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