Carmela Molinaro, Ph.D.

Affiliations: 
2002 Université de Montréal, Montréal, Canada 
Area:
stereoselective synthesis of organic compounds
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"Carmela Molinaro"
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SNBCP

Parents

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Robert Cedergren research assistant (Cell Biology Tree)
André B. Charette grad student 2002 Université de Montréal
 (Carbenoides de zinc et cyclopropanations enantioselectives.)
Timothy F. Jamison post-doc
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Publications

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Wong N, Petronijević F, Hong AY, et al. (2019) Stereocontrolled Synthesis of Arylomycin-Based Gram-Negative Antibiotic GDC-5338. Organic Letters
Molinaro C, Phillips EM, Xiang B, et al. (2019) Synthesis of a CGRP Receptor Antagonist via a Asymmetric Synthesis of 3-Fluoro-4-aminopiperidine. The Journal of Organic Chemistry
Song ZJ, Maligres P, Molinaro C, et al. (2019) Preparation of 2-(2H-Tetrazol-2-yl)benzoic Acids via Regioselective Cu(I) Catalyzed N2 Arylation of Tetrazole Organic Process Research & Development. 23: 2354-2361
Thaisrivongs DA, Miller SP, Molinaro C, et al. (2016) Synthesis of Verubecestat, a BACE1 Inhibitor for the Treatment of Alzheimer's Disease. Organic Letters. 18: 5780-5783
Bungard CJ, Williams PD, Ballard JE, et al. (2016) Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group. Acs Medicinal Chemistry Letters. 7: 702-7
Molinaro C, Scott JP, Shevlin M, et al. (2015) Catalytic, asymmetric, and stereodivergent synthesis of non-symmetric β,β-diaryl-α-amino acids. Journal of the American Chemical Society. 137: 999-1006
Molinaro C, Bulger PG, Lee EE, et al. (2012) CRTH2 antagonist MK-7246: a synthetic evolution from discovery through development. The Journal of Organic Chemistry. 77: 2299-309
Zaghdane H, Boyd M, Colucci J, et al. (2011) New indole amide derivatives as potent CRTH2 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 21: 3471-4
Ouellet SG, Roy A, Molinaro C, et al. (2011) Preparative scale synthesis of the biaryl core of anacetrapib via a ruthenium-catalyzed direct arylation reaction: unexpected effect of solvent impurity on the arylation reaction. The Journal of Organic Chemistry. 76: 1436-9
Molinaro C, Shultz S, Roy A, et al. (2011) A practical synthesis of renin inhibitor MK-1597 (ACT-178882) via catalytic enantioselective hydrogenation and epimerization of piperidine intermediate. The Journal of Organic Chemistry. 76: 1062-71
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