Larry R. Masterson, Ph.D.

Affiliations: 
2008 Chemistry University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Chemical Biology; Physical Chemistry; Environmental Chemistry; Chemical Physics; Experimental Physical Chemistry
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"Larry Masterson"
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SNBCP

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Gianluigi Veglia grad student 2008 UMN
 (Towards the full molecular investigation of protein kinase A mediated catalysis by NMR spectroscopy.)
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Publications

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Kim J, Masterson LR, Cembran A, et al. (2015) Dysfunctional conformational dynamics of protein kinase A induced by a lethal mutant of phospholamban hinder phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 112: 3716-21
Srivastava AK, McDonald LR, Cembran A, et al. (2014) Synchronous opening and closing motions are essential for cAMP-dependent protein kinase A signaling. Structure (London, England : 1993). 22: 1735-43
Chao FA, Morelli A, Haugner JC, et al. (2013) Structure and dynamics of a primordial catalytic fold generated by in vitro evolution. Nature Chemical Biology. 9: 81-3
Cembran A, Masterson LR, McClendon CL, et al. (2012) Conformational equilibrium of N-myristoylated cAMP-dependent protein kinase A by molecular dynamics simulations. Biochemistry. 51: 10186-96
Verardi R, Traaseth NJ, Masterson LR, et al. (2012) Isotope labeling for solution and solid-state NMR spectroscopy of membrane proteins. Advances in Experimental Medicine and Biology. 992: 35-62
Traaseth NJ, Chao FA, Masterson LR, et al. (2012) Heteronuclear Adiabatic Relaxation Dispersion (HARD) for quantitative analysis of conformational dynamics in proteins. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 219: 75-82
Masterson LR, Cembran A, Shi L, et al. (2012) Allostery and binding cooperativity of the catalytic subunit of protein kinase A by NMR spectroscopy and molecular dynamics simulations. Advances in Protein Chemistry and Structural Biology. 87: 363-89
Chao FA, Shi L, Masterson LR, et al. (2012) FLAMEnGO: a fuzzy logic approach for methyl group assignment using NOESY and paramagnetic relaxation enhancement data. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 214: 103-10
Masterson LR, Yu T, Shi L, et al. (2011) cAMP-dependent protein kinase A selects the excited state of the membrane substrate phospholamban. Journal of Molecular Biology. 412: 155-64
Gaffarogullari EC, Masterson LR, Metcalfe EE, et al. (2011) A myristoyl/phosphoserine switch controls cAMP-dependent protein kinase association to membranes. Journal of Molecular Biology. 411: 823-36
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