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Aaron Klug

Affiliations: 
MRC Laboratory of Molecular Biology University of Cambridge, Cambridge, England, United Kingdom 
Area:
Transcription factors, Biochemistry, structural chemistry
Website:
http://nobelprize.org/nobel_prizes/chemistry/laureates/1982/klug.html
Google:
"Aaron Klug"
Bio:

http://www.nasonline.org/member-directory/members/45989.html
The Nobel Prize in Chemistry 1982 was awarded to Aaron Klug "for his development of crystallographic electron microscopy and his structural elucidation of biologically important nucleic acid-protein complexes".

Mean distance: 7.93 (cluster 32)
 
SNBCP
Cross-listing: Physics Tree

Parents

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Douglas R. Hartree grad student Cambridge (Physics Tree)

Children

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Leonid A. Turkevich research assistant 1971-1973 Cambridge (Physics Tree)
Daniela Rhodes grad student
Kenneth C. Holmes grad student 1959 Birkbeck
Linda A. Amos grad student 1975 Cambridge
Alfonso Mondragón grad student 1981-1984 MRC-LMB
Alfonso Mondragón grad student 1981-1984 MRC-LMB
Gérard Bricogne post-doc MRC-LMB
Roger D. Kornberg post-doc MRC-LMB
Wesley I. Sundquist post-doc
Jonathan A. King post-doc 1970 MRC-LMB
Michael Levitt post-doc 1971-1972 MRC-LMB
Jon D. Robertus post-doc 1972-1974 MRC-LMB
Timothy J. Richmond post-doc 1978-1980 MRC-LMB
Raúl Padrón post-doc 1980-1980 MRC-LMB (Cell Biology Tree)
Clarence E. Schutt post-doc 1985 MRC-LMB
William Gregory Scott post-doc 1993-1996 MRC-LMB
Venkat Gopalan post-doc 1998 MRC-LMB
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Publications

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Klug A. (2010) The discovery of zinc fingers and their development for practical applications in gene regulation and genome manipulation. Quarterly Reviews of Biophysics. 43: 1-21
Klug A. (2010) The discovery of zinc fingers and their applications in gene regulation and genome manipulation. Annual Review of Biochemistry. 79: 213-31
Klug A. (2010) From virus structure to chromatin: X-ray diffraction to three-dimensional electron microscopy. Annual Review of Biochemistry. 79: 1-35
Minczuk M, Papworth MA, Miller JC, et al. (2008) Development of a single-chain, quasi-dimeric zinc-finger nuclease for the selective degradation of mutated human mitochondrial DNA. Nucleic Acids Research. 36: 3926-38
Santiago Y, Chan E, Liu PQ, et al. (2008) Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases. Proceedings of the National Academy of Sciences of the United States of America. 105: 5809-14
Shieh JC, Cheng YC, Su MC, et al. (2007) Tailor-made zinc-finger transcription factors activate FLO11 gene expression with phenotypic consequences in the yeast Saccharomyces cerevisiae. Plos One. 2: e746
Lu D, Klug A. (2007) Invariance of the zinc finger module: a comparison of the free structure with those in nucleic-acid complexes. Proteins. 67: 508-12
Minczuk M, Papworth MA, Kolasinska P, et al. (2006) Sequence-specific modification of mitochondrial DNA using a chimeric zinc finger methylase. Proceedings of the National Academy of Sciences of the United States of America. 103: 19689-94
Spillantini MG, Murrell JR, Goedert M, et al. (2006) Mutations in the tau gene (MAPT) in FTDP-17: the family with Multiple System Tauopathy with Presenile Dementia (MSTD). Journal of Alzheimer's Disease : Jad. 9: 373-80
Goedert M, Klug A, Crowther RA. (2006) Tau protein, the paired helical filament and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 9: 195-207
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