Aaron Klug

MRC Laboratory of Molecular Biology University of Cambridge, Cambridge, England, United Kingdom 
Transcription factors, Biochemistry, structural chemistry
"Aaron Klug"

The Nobel Prize in Chemistry 1982 was awarded to Aaron Klug "for his development of crystallographic electron microscopy and his structural elucidation of biologically important nucleic acid-protein complexes".

Mean distance: 7.93 (cluster 32)
Cross-listing: Physics Tree


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Douglas R. Hartree grad student Cambridge (Physics Tree)


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Leonid A. Turkevich research assistant 1971-1973 Cambridge (Physics Tree)
Steven C. Harrison grad student Cambridge University UK
Daniela Rhodes grad student
Kenneth C. Holmes grad student 1959 Birkbeck College
Linda A. Amos grad student 1975 Cambridge
Alfonso Mondragón grad student 1981-1984 MRC-LMB
Gérard Bricogne post-doc MRC-LMB
Harold Erickson post-doc (Cell Biology Tree)
Ellen Gottlieb post-doc MRC-LMB (Cell Biology Tree)
Roger D. Kornberg post-doc MRC-LMB
Wesley I. Sundquist post-doc
Jonathan A. King post-doc 1970 MRC-LMB
Michael Levitt post-doc 1971-1972 MRC-LMB
Jon D. Robertus post-doc 1972-1974 MRC-LMB
Timothy J. Richmond post-doc 1978-1980 MRC-LMB
Raúl Padrón post-doc 1980-1980 MRC-LMB (Cell Biology Tree)
Clarence E. Schutt post-doc 1985 MRC-LMB
Mair E. A. Churchill post-doc 1987-1993 MRC-LMB (Physics Tree)
William Gregory Scott post-doc 1993-1996 MRC-LMB
Venkat Gopalan post-doc 1998 MRC-LMB
Michal Minczuk post-doc 2004-2007 Cambridge


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George Pieczenik collaborator Cambridge (Cell Biology Tree)
BETA: Related publications


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Klug A. (2010) The discovery of zinc fingers and their development for practical applications in gene regulation and genome manipulation. Quarterly Reviews of Biophysics. 43: 1-21
Klug A. (2010) The discovery of zinc fingers and their applications in gene regulation and genome manipulation. Annual Review of Biochemistry. 79: 213-31
Klug A. (2010) From virus structure to chromatin: X-ray diffraction to three-dimensional electron microscopy. Annual Review of Biochemistry. 79: 1-35
Minczuk M, Papworth MA, Miller JC, et al. (2008) Development of a single-chain, quasi-dimeric zinc-finger nuclease for the selective degradation of mutated human mitochondrial DNA. Nucleic Acids Research. 36: 3926-38
Santiago Y, Chan E, Liu PQ, et al. (2008) Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases. Proceedings of the National Academy of Sciences of the United States of America. 105: 5809-14
Shieh JC, Cheng YC, Su MC, et al. (2007) Tailor-made zinc-finger transcription factors activate FLO11 gene expression with phenotypic consequences in the yeast Saccharomyces cerevisiae. Plos One. 2: e746
Lu D, Klug A. (2007) Invariance of the zinc finger module: a comparison of the free structure with those in nucleic-acid complexes. Proteins. 67: 508-12
Minczuk M, Papworth MA, Kolasinska P, et al. (2006) Sequence-specific modification of mitochondrial DNA using a chimeric zinc finger methylase. Proceedings of the National Academy of Sciences of the United States of America. 103: 19689-94
Spillantini MG, Murrell JR, Goedert M, et al. (2006) Mutations in the tau gene (MAPT) in FTDP-17: the family with Multiple System Tauopathy with Presenile Dementia (MSTD). Journal of Alzheimer's Disease : Jad. 9: 373-80
Goedert M, Klug A, Crowther RA. (2006) Tau protein, the paired helical filament and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 9: 195-207
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