Ching-Hsuan Tsai, Ph.D.
Affiliations: | 2000 | Carnegie Mellon University, Pittsburgh, PA |
Area:
molecular biologyGoogle:
"Ching-Hsuan Tsai"Mean distance: 10.51 | S | N | B | C | P |
Parents
Sign in to add mentorChien Ho | grad student | 2000 | Carnegie Mellon | |
(Designing and engineering recombinant hemoglobins as potential hemoglobin -based oxygen carriers.) |
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Publications
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Chi CY, Lin CH, Ho MW, et al. (2016) Clinical manifestations, course, and outcome of patients with neutralizing anti-interferon-γ autoantibodies and disseminated nontuberculous mycobacterial infections. Medicine. 95: e3927 |
Tam MF, Chen J, Tam TC, et al. (2005) Enhanced inhibition of polymerization of sickle cell hemoglobin in the presence of recombinant mutants of human fetal hemoglobin with substitutions at position 43 in the gamma-chain. Biochemistry. 44: 12188-95 |
Manjula BN, Tsai AG, Intaglietta M, et al. (2005) Conjugation of multiple copies of polyethylene glycol to hemoglobin facilitated through thiolation: influence on hemoglobin structure and function. The Protein Journal. 24: 133-46 |
Lin SS, Chou MY, Ho CC, et al. (2005) Study of the viral infections and cytokines associated with recurrent aphthous ulceration. Microbes and Infection / Institut Pasteur. 7: 635-44 |
Balakrishnan G, Tsai CH, Wu Q, et al. (2004) Hemoglobin site-mutants reveal dynamical role of interhelical H-bonds in the allosteric pathway: Time-resolved UV resonance raman evidence for intra-dimer coupling Journal of Molecular Biology. 340: 857-868 |
Manjula BN, Tsai AG, Intaglietta M, et al. (2004) WITHDRAWN: PEGylated hemoglobin: Role of surface configuration of PEG for the modulation of hemoglobin vasoactivity. The Journal of Biological Chemistry |
Srinivasulu S, Manjula BN, Nagel RL, et al. (2004) Hemoglobin Einstein: semisynthetic deletion in the B-helix of the alpha-chain. Protein Science : a Publication of the Protein Society. 13: 1266-75 |
Ho CC, Yang XW, Lee TL, et al. (2003) Activation of p53 signalling in acetylsalicylic acid-induced apoptosis in OC2 human oral cancer cells. European Journal of Clinical Investigation. 33: 875-82 |
Tsai CH, Simplaceanu V, Ho NT, et al. (2003) Site mutations disrupt inter-helical H-bonds (alpha14W-alpha67T and beta15W-beta72S) involved in kinetic steps in the hemoglobin R-->T transition without altering the free energies of oxygenation. Biophysical Chemistry. 100: 131-42 |
Tsai CH, Ho C. (2002) Recombinant hemoglobins with low oxygen affinity and high cooperativity. Biophysical Chemistry. 98: 15-25 |