Marian C. Bryan, Ph.D.
Affiliations: | 2004 | Scripps Research Institute, La Jolla, La Jolla, CA, United States |
Area:
organic chemistryGoogle:
"Marian Bryan"Mean distance: 7.67 | S | N | B | C | P |
Parents
Sign in to add mentor| Chi-Huey Wong | grad student | 2004 | Scripps Institute | |
| (Development and application of glycoarray strategies.) | ||||
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Publications
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| Rajapaksa NS, Gobbi A, Drobnick J, et al. (2020) Discovery of Potent Benzolactam IRAK4 Inhibitors with Robust in Vivo Activity. Acs Medicinal Chemistry Letters. 11: 327-333 |
| Bryan MC, Drobnick J, Gobbi A, et al. (2019) Development of potent and selective pyrazolopyrimidine IRAK4 inhibitors. Journal of Medicinal Chemistry |
| Bryan MC, Rajapaksa N. (2018) Kinase Inhibitors for the Treatment of Immunological Disorders: Recent Advances. Journal of Medicinal Chemistry |
| Aliagas I, Berger R, Goldberg K, et al. (2017) Sustainable Practices in Medicinal Chemistry Part 2: Green by Design. Journal of Medicinal Chemistry |
| Chan BK, Hanan EJ, Bowman K, et al. (2016) Discovery of a Non-Covalent, Mutant-Selective Epidermal Growth Factor Receptor Inhibitor. Journal of Medicinal Chemistry |
| Bryan MC, Burdick DJ, Chan BK, et al. (2016) Pyridones as Highly Selective, Noncovalent Inhibitors of T790M Double Mutants of EGFR. Acs Medicinal Chemistry Letters. 7: 100-4 |
| Hanan EJ, Baumgardner M, Bryan MC, et al. (2015) 4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase. Bioorganic & Medicinal Chemistry Letters |
| Epstein O, Bryan MC, Cheng AC, et al. (2014) Lead optimization and modulation of hERG activity in a series of aminooxazoline xanthene β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors. Journal of Medicinal Chemistry. 57: 9796-810 |
| Bryan MC, Hein CD, Gao H, et al. (2013) Disubstituted 1-aryl-4-aminopiperidine library synthesis using computational drug design and high-throughput batch and flow technologies. Acs Combinatorial Science. 15: 503-11 |
| Bryan MC, Falsey JR, Frohn M, et al. (2013) N-substituted azaindoles as potent inhibitors of Cdc7 kinase. Bioorganic & Medicinal Chemistry Letters. 23: 2056-60 |