Michael J. Rishel, Ph.D.

Affiliations: 
2004 University of Virginia, Charlottesville, VA 
Area:
Natural products, Bleomycin
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"Michael Rishel"
Mean distance: 9.38
 
SNBCP

Parents

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Sidney M. Hecht grad student 2004 UVA
 (Synthesis of DNA damaging agents.)
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Publications

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Yu Z, Paul R, Bhattacharya C, et al. (2015) Structural features facilitating tumor cell targeting and internalization by bleomycin and its disaccharide. Biochemistry. 54: 3100-9
Yang H, Miao Q, Johnson BF, et al. (2014) A simple route to [11C]N-Me labeling of aminosuberic acid for proof of feasibility imaging of the x(C)⁻ transporter. Bioorganic & Medicinal Chemistry Letters. 24: 5512-5
Madathil MM, Bhattacharya C, Yu Z, et al. (2014) Modified bleomycin disaccharides exhibiting improved tumor cell targeting. Biochemistry. 53: 6800-10
Schroeder BR, Ghare MI, Bhattacharya C, et al. (2014) The disaccharide moiety of bleomycin facilitates uptake by cancer cells. Journal of the American Chemical Society. 136: 13641-56
Bhattacharya C, Yu Z, Rishel MJ, et al. (2014) The carbamoylmannose moiety of bleomycin mediates selective tumor cell targeting. Biochemistry. 53: 3264-6
Natarajan A, Boden EP, Burns A, et al. (2014) Synthesis, chemical reactivity, and photophysical properties of 2′,7′ phenylated rhodamine dyes Tetrahedron Letters. 55: 4222-4226
Yu Z, Schmaltz RM, Bozeman TC, et al. (2013) Selective tumor cell targeting by the disaccharide moiety of bleomycin. Journal of the American Chemical Society. 135: 2883-6
Rishel MJ, Thomas CJ, Tao ZF, et al. (2003) Conformationally constrained analogues of bleomycin A5. Journal of the American Chemical Society. 125: 10194-205
Leitheiser CJ, Smith KL, Rishel MJ, et al. (2003) Solid-phase synthesis of bleomycin group antibiotics. Construction of a 108-member deglycobleomycin library. Journal of the American Chemical Society. 125: 8218-27
Thomas CJ, Chizhov AO, Leitheiser CJ, et al. (2002) Solid-phase synthesis of bleomycin A(5) and three monosaccharide analogues: exploring the role of the carbohydrate moiety in RNA cleavage. Journal of the American Chemical Society. 124: 12926-7
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