Adam T. Hoye, Ph.D.

Affiliations: 
2010 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Chemical Biology
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Peter Wipf grad student 2010 University of Pittsburgh
 (Synthesis of Natural and Non-Natural Polycylic Alkaloids.)
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Publications

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Christner S, Guo J, Parise RA, et al. (2017) Liquid chromatography-tandem mass spectrometric assay for the quantitation of the novel radiation protective agent and radiation mitigator JP4-039 in murine plasma. Journal of Pharmaceutical and Biomedical Analysis. 150: 169-175
Liu Q, An C, TenDyke K, et al. (2016) Design, Synthesis, and Evaluation of Irciniastatin Analogues: Simplification of the Tetrahydropyran Core and the C(11) Substituents. The Journal of Organic Chemistry
Lou K, Yao Y, Hoye AT, et al. (2014) Brain-penetrant, orally bioavailable microtubule-stabilizing small molecules are potential candidate therapeutics for Alzheimer's disease and related tauopathies. Journal of Medicinal Chemistry. 57: 6116-27
Martinez-Solorio D, Hoye AT, Nguyen MH, et al. (2013) The design, synthesis and validation of recoverable and readily reusable siloxane transfer agents for Pd-catalyzed cross-coupling reactions. Organic Letters. 15: 2454-7
An C, Jurica JA, Walsh SP, et al. (2013) Total synthesis of (+)-irciniastatin A (a.k.a. psymberin) and (-)-irciniastatin B. The Journal of Organic Chemistry. 78: 4278-96
An C, Hoye AT, Smith AB. (2012) Total synthesis of (-)-irciniastatin B and structural confirmation via chemical conversion to (+)-irciniastatin A (psymberin). Organic Letters. 14: 4350-3
Smith AB, Hoye AT, Martinez-Solorio D, et al. (2012) Unification of anion relay chemistry with the Takeda and Hiyama cross-coupling reactions: identification of an effective silicon-based transfer agent. Journal of the American Chemical Society. 134: 4533-6
Hoye AT, Wipf P. (2011) Total synthesis of (-)-sessilifoliamide C and (-)-8-epi-stemoamide. Organic Letters. 13: 2634-7
Jiang J, Belikova NA, Hoye AT, et al. (2008) A mitochondria-targeted nitroxide/hemigramicidin S conjugate protects mouse embryonic cells against gamma irradiation. International Journal of Radiation Oncology, Biology, Physics. 70: 816-25
Hoye AT, Davoren JE, Wipf P, et al. (2008) Targeting mitochondria. Accounts of Chemical Research. 41: 87-97
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