Frederick Cohen, Ph.D.

Affiliations: 
2001 University of California, Irvine, Irvine, CA 
Area:
synthesis of natural products
Google:
"Frederick Cohen"
Mean distance: 8.24
 
SNBCP

Parents

Sign in to add mentor
Larry E. Overman grad student 2001 UC Irvine
 (Enantioselective total synthesis of batzelladine F: Structural revision and stereochemical definition.)
BETA: Related publications

Publications

You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Kroeck KG, Sacco MD, Smith EW, et al. (2019) Discovery of dual-activity small-molecule ligands of Pseudomonas aeruginosa LpxA and LpxD using SPR and X-ray crystallography. Scientific Reports. 9: 15450
Krause KM, Haglund CM, Hebner C, et al. (2019) Potent LpxC Inhibitors with Activity Against Multi-Drug Resistant . Antimicrobial Agents and Chemotherapy
Wertz I, Kategaya L, Lello PD, et al. (2018) Abstract SY23-03: Development and mechanistic characterization of USP7 deubiquitinase inhibitors Cancer Research. 78
Di Lello P, Pastor R, Murray JM, et al. (2017) Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and In-Silico Techniques. Journal of Medicinal Chemistry
Kategaya L, Di Lello P, Rougé L, et al. (2017) USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature
Patel S, Cohen F, Dean BJ, et al. (2015) Discovery of dual leucine zipper kinase (DLK, MAP3K12) inhibitors with activity in neurodegeneration models. Journal of Medicinal Chemistry. 58: 401-18
Heise CE, Murray J, Augustyn KE, et al. (2012) Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6. Plos One. 7: e50864
Cohen F, Bergeron P, Blackwood E, et al. (2011) Potent, selective, and orally bioavailable inhibitors of mammalian target of rapamycin (mTOR) kinase based on a quaternary substituted dihydrofuropyrimidine. Journal of Medicinal Chemistry. 54: 3426-35
Cohen F, Overman LE. (2006) Enantioselective total synthesis of batzelladine F and definition of its structure. Journal of the American Chemical Society. 128: 2604-8
Cohen F, Overman LE. (2006) Evolution of a strategy for the synthesis of structurally complex batzelladine alkaloids. Enantioselective total synthesis of the proposed structure of batzelladine F and structural revision. Journal of the American Chemical Society. 128: 2594-603
See more...