Adam K. Charnley, Ph.D.
Affiliations: | 2005 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Natural product synthesisGoogle:
"Adam Charnley"Mean distance: 8.15
Parents
Sign in to add mentor| Amos B. Smith, III | grad student | 2005 | Penn | |
| (Expanding the scope and utility of the pyrrolinone peptidomimetic scaffold: Structural, biological and methodological advances.) | ||||
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Publications
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| Smith AB, Charnley AK, Hirschmann R. (2011) Pyrrolinone-based peptidomimetics. "Let the enzyme or receptor be the judge". Accounts of Chemical Research. 44: 180-93 |
| Smith AB, Xiong H, Charnley AK, et al. (2010) Design, synthesis, and structural analysis of D,L-mixed polypyrrolinones. 2. Macrocyclic hexapyrrolinones. Organic Letters. 12: 2994-7 |
| Smith AB, Wang W, Charnley AK, et al. (2010) Design, synthesis, and structural analysis of D,L-mixed polypyrrolinones. 1. From nonpeptide peptidomimetics to nanotubes. Organic Letters. 12: 2990-3 |
| Bagchi S, Charnley AK, Smith Iii AB, et al. (2009) Equilibrium exchange processes of the aqueous tryptophan dipeptide. The Journal of Physical Chemistry. B. 113: 8412-7 |
| Bagchi S, Kim YS, Charnley AK, et al. (2007) Two-dimensional infrared investigation of N-acetyl tryptophan methyl amide in solution. The Journal of Physical Chemistry. B. 111: 3010-8 |
| Smith AB, Charnley AK, Harada H, et al. (2006) Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2' side chains. Bioorganic & Medicinal Chemistry Letters. 16: 859-63 |
| Smith AB, Charnley AK, Mesaros EF, et al. (2005) Design, synthesis, and binding affinities of pyrrolinone-based somatostatin mimetics. Organic Letters. 7: 399-402 |
| Fang C, Wang J, Kim YS, et al. (2004) Two-dimensional infrared spectroscopy of isotopomers of an alanine rich α-helix Journal of Physical Chemistry B. 108: 10415-10427 |
| Rubtsov IV, Wang J, Fang C, et al. (2004) Multidimensional and dual frequency infrared analogues of NMR. Applications to peptides and isotopomers of secondary structures Femtochemistry and Femtobiology: Ultrafast Events in Molecular Science. 365-372 |
| Smith AB, Cantin LD, Pasternak A, et al. (2003) Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors. Journal of Medicinal Chemistry. 46: 1831-44 |