Douglas C. Beshore, Ph.D.
Affiliations: | 2007 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Natural product synthesisGoogle:
"Douglas Beshore"Mean distance: 8.15 | S | N | B | C | P |
Parents
Sign in to add mentor| Amos B. Smith, III | grad student | 2007 | Penn | |
| (Total syntheses of (+)-lyconadin A and (-)-lyconadin B.) | ||||
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Publications
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| Beshore DC, Haidle AM, Arasappan A, et al. (2022) Building a Culture of Medicinal Chemistry Knowledge Sharing. Journal of Medicinal Chemistry |
| Beshore DC, Johnson AW, DiPardo RM, et al. (2016) 2,5-Disubstituted Pyrazolo[4,3-c]cinnolin-3-ones Journal of Heterocyclic Chemistry. 54: 1558-1571 |
| Beshore DC, DiPardo RM, Kuduk SD. (2010) Preparation of 2,4,5-trisubstituted pyrazolo[4,3-c]quinolin-3-ones Tetrahedron Letters. 51: 970-973 |
| Smith AB, Atasoylu O, Beshore DC. (2009) Construction of 5,6-Ring Fused 2-Pyridones: An Effective Annulation Tactic Achieved in Water. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 2009: 2643-2646 |
| Beshore DC, Smith AB. (2008) The lyconadins: enantioselective total syntheses of (+)-lyconadin A and (-)-lyconadin B. Journal of the American Chemical Society. 130: 13778-89 |
| Bell IM, Gallicchio SN, Abrams M, et al. (2002) 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. Journal of Medicinal Chemistry. 45: 2388-409 |
| Bell IM, Gallicchio SN, Abrams M, et al. (2001) Design and biological activity of (S)-4-(5-([1-(3-chlorobenzyl)-2-oxopyrrolidin-3-ylamino]methyl)imidazol-1-ylmethyl)benzonitrile, a 3-aminopyrrolidinone farnesyltransferase inhibitor with excellent cell potency. Journal of Medicinal Chemistry. 44: 2933-49 |
| Beshore DC, Bell IM, Dinsmore CJ, et al. (2001) Evaluation of amino acid-based linkers in potent macrocyclic inhibitors of farnesyl-protein transferase. Bioorganic & Medicinal Chemistry Letters. 11: 1817-21 |
| Bell IM, Beshore DC, Gallicchio SN, et al. (2000) Efficient synthesis of 1-heterocyclic-3-aminopyrrolidinones Tetrahedron Letters. 41: 1141-1145 |
| Beshore DC, Dinsmore CJ. (2000) Efficient synthesis of unsymmetrical 1,4-disubstituted-2,3-diketopiperazines via tandem reductive amination-cyclization Tetrahedron Letters. 41: 8735-8739 |